NMR methodology for the study of nucleic acids

被引：51

作者：

Zídek, L ^{[1
]}

Stefl, R ^{[1
]}

Sklenár, V ^{[1
]}

机构：

[1] Masaryk Univ, Natl Ctr Biomol Res, Brno 61137, Czech Republic

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(00)00218-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During the past few years, NMR methodology for the study of nucleic acids has benefited from new developments that greatly improved state-of-the-art technology for the precise determination of three-dimensional structures. Substantial progress has been made in designing experimental protocols for the measurement of residual dipolar couplings, in sensitivity optimization of triple-resonance experiments and in detection of hydrogen bonds and in developing computational methods for structure refinement using NMR restraints.

引用

页码：275 / 281

页数：7

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