Failure of asparagine (ASN) depletion, not inadequate asparaginase (ASNase) activity, predicts relapse in standard risk (SR) childhood acute lymphoblastic leukemia (ALL): A Children's Oncology Group (COG) report

被引：3
|
作者：
Avramis, Vassilios I. [1 ]
Holcenberg, John S. [1 ]
Ettinger, Alice G. [1 ]
Stork, Linda C. [1 ]
La, Mei [1 ]
Gaynon, Paul S. [1 ]
机构：
[1] Childrens Oncol Grp, Arcadia, CA USA
来源：
BLOOD | 2007年 / 110卷 / 11期
关键词：
D O I：
10.1182/blood.V110.11.588.588
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
588
引用
收藏
页码：181A / 181A
页数：1
相关论文
共 50 条
  • [1] Asparagine (ASN) depletion and treatment response in childhood acute lymphoblastic leukemia (ALL) after an early marrow relapse: A children's cancer group
    Gaynon, PS
    Harris, RE
    Stram, DO
    Atlman, AJ
    Bostrom, BC
    Breneman, J
    Hawks, R
    Steele, D
    Trigg, ME
    Uckun, FM
    Zipf, T
    Cohen, LJ
    Fu, C
    Avramis, VI
    BLOOD, 1999, 94 (10) : 628A - 628A
  • [2] Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group (COG)
    Gupta, S.
    Wang, C.
    Raetz, E.
    Schore, R.
    Salzer, W.
    Larsen, E.
    Maloney, K.
    Mattano, L.
    Carroll, W.
    Winick, N.
    Hunger, S.
    Loh, M.
    Devidas, M.
    PEDIATRIC BLOOD & CANCER, 2019, 66 : S7 - S8
  • [3] Asparagine (Asn) deamination in children with higher risk acute lymphoblastic leukemia (HR ALL) at lower asparaginase (ASNase) activity levels (CCG-1961 study).
    Panosyan, E
    Avramis, I
    Seibel, NL
    Grigoryan, R
    Gaynon, PS
    Sather, H
    Siegel, SE
    Avramis, VI
    BLOOD, 2002, 100 (11) : 760A - 760A
  • [4] Determinants of Survival After First Relapse of Childhood Acute Lymphoblastic Leukemia (ALL): A Children's Oncology Group (COG) Study
    Loh, M.
    Rheingold, S.
    Bhojwani, D.
    Ji, L.
    Xu, X.
    Devidas, M.
    Brown, P.
    Gore, L.
    Winick, N.
    Carroll, W.
    Raetz, E.
    Hunger, S.
    PEDIATRIC BLOOD & CANCER, 2019, 66 : S8 - S8
  • [5] Sex-Based Disparities in Outcome in Childhood Acute Lymphoblastic Leukemia (ALL): A Children's Oncology Group (COG) Report
    Gupta, Sumit
    Teachey, David T.
    Devidas, Meenakshi
    Chen, Zhiguo
    Dunsmore, Kimberly P.
    Larsen, Eric C.
    Maloney, Kelly
    Mattano, Leonard A.
    Winter, Stuart S.
    Carroll, Andrew J.
    Heerema, Nyla A.
    Borowitz, Michael J.
    Wood, Brent L.
    Carroll, William L.
    Winick, Naomi J.
    Raetz, Elizabeth A.
    Loh, Mignon L.
    Hunger, Stephen P.
    BLOOD, 2020, 136
  • [6] Trends in body mass index (BMI) during and after treatment for standard risk (SR) acute lymphoblastic leukemia (ALL): A report from the Children's Oncology Group (COG)
    Lindemulder, Susan Joy
    Stork, Linda C.
    Bostrom, Bruce C.
    Lu, Xiaomin
    Devidas, Meenakshi
    Neglia, Joseph Philip
    Kadan-Lottick, Nina
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [7] Minimal residual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) in relapse. A children's oncology group (COG) study.
    Borowitz, MJ
    Devidas, M
    Hunger, SP
    Carroll, WL
    Raetz, E
    BLOOD, 2004, 104 (11) : 96A - 96A
  • [8] PROLONGED ASPARAGINE (ASN) DEPLETION AFTER HIGH-DOSE ASPARAGINASE (HDA) THERAPY IN CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA (ALL)
    FALLER, DV
    BEARDSLEY, GP
    MIKITA, T
    SALLAN, S
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1985, 26 (MAR): : 156 - 156
  • [9] Outstanding Outcome for Children with Standard Risk-Low (SR-Low) Acute Lymphoblastic Leukemia (ALL) and No Benefit to Intensified Peg-Asparaginase (PEG-ASNase) Therapy: Results of Children's Oncology Group (COG) Study AALL0331
    Mattano, Leonard A.
    Devidas, Meenakshi
    Friedmann, Alison M.
    Raetz, Elizabeth A.
    Loh, Mignon
    Buckley, Patrick
    Borowitz, Michael J.
    Carroll, Andrew J.
    Gastier-Foster, Julie
    Heerema, Nyla A.
    Kadan-Lottick, Nina
    Matloub, Yousif
    Marshall, David T.
    Stork, Linda C.
    Wood, Brent L.
    Winick, Naomi J.
    Hunger, Stephen
    Carroll, William L.
    Maloney, Kelly
    BLOOD, 2014, 124 (21)
  • [10] Risk-adapted therapy for children with acute lymphoblastic leukemia (ALL): The children's oncology group (COG) approach
    Carroll, W. L.
    Hunger, S. P.
    Borowitz, M. J.
    Bhojwani, D.
    Willman, C. L.
    Devidas, M.
    Schultz, K.
    Loh, M. L.
    Raetz, E. A.
    ANNALS OF HEMATOLOGY, 2008, 87 : S42 - S44
12345