Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum

被引:47
|
作者
Morteza-Semnani, K [1 ]
Amin, G
Shidfar, MR
Hadizadeh, H
Shafiee, A
机构
[1] Mazandaran Univ Med Sci, Fac Pharm, Dept Med Chem, Sari, Iran
[2] Univ Tehran Med Sci, Fac Pharm, Dept Pharmacognosy, Tehran, Iran
[3] Univ Tehran Med Sci, Fac Med, Dept Microbiol, Tehran, Iran
[4] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, Tehran, Iran
关键词
Glaucium oxylobum; antifungal activity; alkaloids;
D O I
10.1016/S0367-326X(03)00113-8
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The methanolic, extract and total alkaloids of the aerial parts of Glaucium oxylobum exhibited good activity against Microsporum gypseum, Microsporum canis, Trichophyton mentagrophytes and Epidermophyton floccosum. Four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:493 / 496
页数:4
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