Association of the hSERT and SLC6A4 polymorphic markers of the serotonin transporter gene with schizophrenia in two ethnic groups

被引：4
|
作者：
Zainullina, AG [1 ]
Juriev, EB [1 ]
Bikbulatova, SR [1 ]
Khusnutdinova, EK [1 ]
机构：
[1] Russian Acad Sci, Ufa Res Ctr, Inst Biochem & Genet, Ufa 450054, Russia
来源：
MOLECULAR BIOLOGY | 2003年 / 37卷 / 04期
关键词：
serotonin transporter gene; genetic markers; genetic predisposition; polymerase chain reaction; schizophrenia; human population;
D O I：
10.1023/A:1025123024228
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Insertion/deletion and VNTR polymorphisms of the serotonin transporter gene were tested for association with schizophrenia in patients of different ethnicity. A difference in genetic predisposition was observed for continuous and shift-like schizophrenia forms, the former tending to be associated with genotype 12/12 in Tatars and L/L in Russians.
引用
收藏
页码：508 / 512
页数：5
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