Hydrogel formation via cell crosslinking

被引:94
|
作者
Lee, KY
Kong, HJ
Larson, RG
Mooney, DJ [1 ]
机构
[1] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Biol & Mat Sci, Ann Arbor, MI 48109 USA
关键词
D O I
10.1002/adma.200305406
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
It is demonstrated that cells can be utilized as a crosslinker to form network structures from polymers. The properties of these systems can be interpreted with classical network theory. This approach can be useful to determine various parameters related to cell receptor-ligand binding (see Figure), such as the number of bonds, as well as to suggest a unique means to the delivery of cells for therapeutic purposes.
引用
收藏
页码:1828 / 1832
页数:5
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