Pharmacological Effects and Chemical Constituents of Bupleururn

被引：35

作者：

Sun, Peng ^{[1
,2
]}

Li, Yijie ^{[1
]}

Wei, Sheng ^{[1
]}

Zhao, Tingting ^{[1
]}

Wang, Yang ^{[3
]}

Song, Chunhong ^{[1
]}

Xue, Ling ^{[1
,2
]}

Wang, Fushun ^{[4
]}

Xiao, Lingyun ^{[5
]}

Wu, Jibiao ^{[1
]}

Qiao, Mingqi ^{[1
]}

机构：

[1] Shandong Univ Tradit Chinese Med, Minist Educ, Key Lab Tradit Chinese Med Class Theory, Jinan 250355, Shandong, Peoples R China

[2] Shandong Univ Tradit Chinese Med, Sch Pharm, Jinan 250355, Shandong, Peoples R China

[3] Cent S Univ, Inst Integrated Tradit Chinese & Western Med, Xiangya Hosp, Lab Ethnopharmacol, Changsha 410008, Hunan, Peoples R China

[4] Nanjing Univ Chinese Med, Coll Psychol, Nanjing 210023, Jiangsu, Peoples R China

[5] Huazhong Univ Sci & Technol, Joint Lab Res Modern Preparat Technol, Wuhan 430071, Hubei, Peoples R China

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2019年 / 19卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Radix Bupleuri; pharmacological action; chemical composition; Chinese medicine; flavonoids; phenyl propanol derivatives; triterpenoid saponins; volatile oils; NANOARCHITECTONICS; SAIKOSAPONIN; CHINENSE;

D O I：

10.2174/1871520618666180628155931

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Radix Bupleuri has been used in traditional Chinese medicine for thousands of years, with confirmed curative effects. This plant is also used in healthy food and cosmetics. A recent increase in studies of Radix Bupleuri's chemical constituents (mainly comprising flavonoids, lignins, phenyl propanol derivatives, triterpenoid saponins, and volatile oils) and pharmacological effects motivates the aim of the present study: to review the chemical components and pharmacological effects of Radix Bupleuri. Our review found that Radix Bupleuri exhibits diverse pharmacological effects. More than 281 components have been isolated from Radix Bupleuri, including 15 flavonoids, 430 lignins, 12 phenyl propanol derivatives, 66 triterpenoid saponins, and 158 volatile oils.

引用

页码：34 / 55

页数：22

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