EFFECT OF FOOD ON PHARMACOKINETICS AND SAFETY OF DA-8010, A NOVEL SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST, IN HEALTHY SUBJECTS

被引:0
|
作者
Khwarg, J. [1 ]
Yang, E. [1 ]
Chung, W. [1 ]
Park, S. [1 ]
Jang, I [1 ]
Cho, J. [1 ]
Ryu, C. [2 ]
Lee, D. [2 ]
Lee, M. [2 ]
Kim, H. [3 ]
Lee, S. [1 ]
机构
[1] Seoul Natl Univ, Dept Clin Pharmacol & Therapeut, Coll Med & Hosp, Seoul, South Korea
[2] Dong A ST Res Inst, Yongin, South Korea
[3] Dong A ST Co Ltd, Seoul, South Korea
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
31
引用
收藏
页码:S29 / S30
页数:2
相关论文
共 50 条
  • [1] PHARMACOLOGICAL PROFILE OF DA-8010, A NOVEL BLADDER SELECTIVE MUSCARINIC RECEPTOR 3 ANTAGONIST FOR TREATMENT OF OVERACTIVE BLADDER
    Lee, Min Jung
    Moon, Jun-Hwan
    Park, Hyun-Min
    Lee, Hyung Keun
    Cho, Jong Hwan
    Choi, Sung Hak
    Im, Weonbin
    JOURNAL OF UROLOGY, 2016, 195 (04): : E416 - E417
  • [2] Pharmacological characterization of DA-8010, a novel muscarinic receptor antagonist selective for urinary bladder over salivary gland
    Lee, Min Jung
    Moon, Jun-Hwan
    Lee, Hyung Keun
    Cho, Chong Hwan
    Choi, Sung Hak
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 843 : 240 - 250
  • [3] The effects of oral administration of the novel muscarinic receptor antagonist DA-8010 on overactive bladder in rat with bladder outlet obstruction
    Jin Bong Choi
    Seung Hwan Jeon
    Eun Bi Kwon
    Woong Jin Bae
    Hyuk Jin Cho
    U-Syn Ha
    Sung-Hoo Hong
    Ji Youl Lee
    Sae Woong Kim
    BMC Urology, 20
  • [4] The effects of oral administration of the novel muscarinic receptor antagonist DA-8010 on overactive bladder in rat with bladder outlet obstruction
    Choi, Jin Bong
    Jeon, Seung Hwan
    Kwon, Eun Bi
    Bae, Woong Jin
    Cho, Hyuk Jin
    Ha, U-Syn
    Hong, Sung-Hoo
    Lee, Ji Youl
    Kim, Sae Woong
    BMC UROLOGY, 2020, 20 (01)
  • [5] Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects
    Khwarg, Juyoung
    Chung, Woo Kyung
    Lee, Soyoung
    Yang, Eunsol
    Ryu, Chaelim
    Lee, Dae Young
    Lee, Min Jung
    Jang, In-Jin
    Yu, Kyung-Sang
    Lee, Seunghwan
    CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2024, 13 (02): : 128 - 133
  • [6] Safety, tolerability, and pharmacokinetics of single and multiple ascending Oral doses of DA-8010 in healthy subjects: First-in-human phase I study
    Lee, Dae Young
    Lee, Min Jung
    Ryu, Chaelim
    Lee, Heewon
    Brooks, Ashley
    PHARMACOLOGY RESEARCH & PERSPECTIVES, 2023, 11 (01):
  • [7] Safety, tolerability, pharmacokinetics and metabolism of balovaptan, a selective vasopressin 1a receptor antagonist, in healthy subjects
    Derks, M.
    Lennon-Chrimes, S.
    Guenther, A.
    Squassante, L.
    Wandel, C.
    Paehler, A.
    Kletzl, H.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2019, 29 : S162 - S162
  • [8] Combination therapy with PDE5 inhibitor and the novel muscarinic antagonist DA-8010 for benign prostatic hyperplasia with lower urinary tract symptoms: an experimental rat model
    Choi, Jin Bong
    Jeon, Seung Hwan
    Kwon, Eun Bi
    Han, Kyu Hun
    Bae, Woong Jin
    Kim, Sae Woong
    INTERNATIONAL JOURNAL OF UROLOGY, 2020, 27 : 135 - 135
  • [9] Efficacy and Safety of DA-8010, a Novel M3 Antagonist, in Patients With Overactive Bladder: A Randomized, Double-Blind Phase 2 Study
    Son, Hee Seo
    Oh, Cheol Young
    Choo, Myung-Soo
    Kim, Hyeong Gon
    Kim, Joon Chul
    Lee, Kyu-Sung
    Shin, Dong Gil
    Cho, Sung Yong
    Jeong, Seong Jin
    Seo, Ju Tae
    Yoon, Hana
    Moon, Hong Sang
    Kim, Jang Hwan
    INTERNATIONAL NEUROUROLOGY JOURNAL, 2022, 26 (02) : 119 - 128
  • [10] Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects
    Gao, Huaye
    Li, Jintong
    Chen, Xiaoping
    Sun, Zhanguo
    Cui, Gang
    Cheng, Minlu
    Ding, Li
    FRONTIERS IN PHARMACOLOGY, 2022, 13