Ternary complexes between DNA, polyamine, and cucurbituril: A modular approach to DNA-binding molecules

被引：0

作者：

Isobe, H

Tomita, N

Lee, JW

Kim, HJ

Kim, K

Nakamura, E ^{[1
]}

机构：

[1] Univ Tokyo, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

[2] Pohang Univ Sci & Technol, Dept Chem, Div Mol & Life Sci, POSTECH, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, POSTECH, Pohang 790784, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2000年 / 39卷 / 23期

关键词：

DNA recognition; Intercalation; Rotaxanes; Supramolecular chemistry;

D O I：

10.1002/1521-3773(20001201)39:23<4257::AID-ANIE4257>3.0.CO;2-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Attachment of small molecules to large biomolecules can occur through a supramolecular three-body modular-binding scheme (see scheme). This approach allows cucurbit[6]uril (C), which normally cannot bind to DNA, to be attached to double-stranded DNA (A) through a linker molecule (B) containing both an acridine moiety (which binds to DNA) and a spermine moiety (which binds cucurbit[6]uril).

引用

页码：4257 / +

页数：5

共 50 条

[1] DNA-binding hemoproteins tethering polyamine interface
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan
不详
Bull. Chem. Soc. Jpn., 4 (375-377):
[2] SYNTHESIS AND DNA-BINDING PROPERTIES OF POLYAMINE ANALOGS
EDWARDS, ML
SNYDER, RD
STEMERICK, DM
JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (08) : 2414 - 2420
[3] DNA-Binding Hemoproteins Tethering Polyamine Interface
Onoda, Akira
Nagai, Hirokazu
Koga, Satoe
Hayashi, Takashi
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2010, 83 (04) : 375 - 377
[4] Immobilized DNA-binding assay, an approach for in vitro DNA-binding assay
Kim, JH
ANALYTICAL BIOCHEMISTRY, 2004, 334 (02) : 401 - 402
[5] Double duty for DNA-binding molecules
不详
CHEMICAL & ENGINEERING NEWS, 2007, 85 (07) : 69 - 69
[6] Programmable DNA-binding small molecules
Blackledge, Meghan S.
Melander, Christian
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (20) : 6101 - 6114
[7] CORRELATION BETWEEN CYTOTOXICITY AND DNA-BINDING OF POLYPYRIDYL RUTHENIUM COMPLEXES
NOVAKOVA, O
KASPARKOVA, J
VRANA, O
VANVLIET, PM
REEDIJK, J
BRABEC, V
BIOCHEMISTRY, 1995, 34 (38) : 12369 - 12378
[8] CASTING FOR MULTICOMPONENT DNA-BINDING COMPLEXES
WRIGHT, WE
FUNK, WD
TRENDS IN BIOCHEMICAL SCIENCES, 1993, 18 (03) : 77 - 80
[9] Structure and Affinity of Complexes between the DNA-Binding Domain of Swi4 and DNA
Afonin D.A.
Geras’kina O.V.
Loseva T.V.
Kirpichnikov M.P.
Studitsky V.M.
Feofanov A.V.
Biophysics, 2022, 67 (5) : 700 - 707
[10] DNA-binding molecules based on the PNA backbone
Woski, SA
Challa, H
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 217 : U121 - U121

← 1 2 3 4 5 →