Atherosclerosis in HIV Patients: What Do We Know so Far?

被引:11
|
作者
Poznyak, Anastasia V. [1 ]
Bezsonov, Evgeny E. [2 ,3 ,4 ]
Borisov, Evgeny E. [2 ]
Grechko, Andrey V. [5 ]
Kartuesov, Andrey G. [3 ]
Orekhov, Alexander N. [1 ,2 ,3 ]
机构
[1] Atherosclerosis Res Inst, Skolkovo Innovat Ctr, Moscow 121609, Russia
[2] AP Avtsyn Res Inst Human Morphol, 3 Tsyurupa St, Moscow 117418, Russia
[3] Inst Gen Pathol & Pathophysiol, Lab Angiopathol, 8 Baltiiskaya St, Moscow 125315, Russia
[4] Sechenov Univ, Dept Biol & Gen Genet, IM Sechenov First Moscow State Med Univ, 8 Izmailovsky Blvd, Moscow 105043, Russia
[5] Fed Res & Clin Ctr Intens Care Med & Rehabilitol, 14-3 Solyanka St, Moscow 109240, Russia
基金
俄罗斯科学基金会;
关键词
atherosclerosis; HIV; immunity; ENDOPLASMIC-RETICULUM STRESS; ANTIRETROVIRAL THERAPY; CARDIOVASCULAR-DISEASE; PLASMA TRIGLYCERIDES; NLRP3; INFLAMMASOME; INFECTED PATIENTS; STATIN USE; RISK; IMMUNODEFICIENCY; DYSLIPIDEMIA;
D O I
10.3390/ijms23052504
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis.
引用
收藏
页数:14
相关论文
共 50 条
  • [1] HIV and neoplasms: What do we know so far?
    de Souza, Thais Faria
    Sym, Yasmin Vianna
    Chehter, Ethel Zimberg
    EINSTEIN-SAO PAULO, 2023, 21 : eRW0231
  • [2] Leishmaniasis in transplant patients: what do we know so far?
    Monge-Maillo, Begona
    Lopez-Velez, Rogelio
    CURRENT OPINION IN INFECTIOUS DISEASES, 2024, 37 (05) : 342 - 348
  • [3] Amyloidogenesis: What Do We Know So Far?
    Alraawi, Zeina
    Banerjee, Nayan
    Mohanty, Srujana
    Kumar, Thallapuranam Krishnaswamy Suresh
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (22)
  • [4] ASPHALTENES: WHAT DO WE KNOW SO FAR
    Al-Qasim, Abdulaziz S.
    Alasker, Mohammed
    PROCEEDINGS OF THE ASME 36TH INTERNATIONAL CONFERENCE ON OCEAN, OFFSHORE AND ARCTIC ENGINEERING, 2017, VOL 8, 2017,
  • [5] Trichotillomania: What Do We Know So Far?
    Melo, Daniel Fernandes
    Lima, Caren dos Santos
    Piraccini, Bianca Maria
    Tosti, Antonella
    SKIN APPENDAGE DISORDERS, 2022, 8 (01) : 1 - 7
  • [6] Probiotics: What Do We Know So Far?
    Steinberg, Skylar
    Hazan, Sabine
    PRACTICAL GASTROENTEROLOGY, 2018, 42 (10) : 68 - 70
  • [7] Crowdfunding: What Do We Know So Far?
    Jovanovic, Tanja
    INTERNATIONAL JOURNAL OF INNOVATION AND TECHNOLOGY MANAGEMENT, 2019, 16 (01)
  • [8] PEComa: what do we know so far?
    Hornick, JL
    Fletcher, CDM
    HISTOPATHOLOGY, 2006, 48 (01) : 75 - 82
  • [9] Thirst in patients on chronic hemodialysis: What do we know so far?
    Bossola, Maurizio
    Calvani, Riccardo
    Marzetti, Emanuele
    Picca, Anna
    Antocicco, Emanuela
    INTERNATIONAL UROLOGY AND NEPHROLOGY, 2020, 52 (04) : 697 - 711
  • [10] Thirst in patients on chronic hemodialysis: What do we know so far?
    Maurizio Bossola
    Riccardo Calvani
    Emanuele Marzetti
    Anna Picca
    Emanuela Antocicco
    International Urology and Nephrology, 2020, 52 : 697 - 711