Identification of Clenbuterol by MALDI-TOF Mass Spectrometry

被引：0
|
作者：
Huo, Q. [1 ,2 ]
Zhou, T. [1 ]
He, J. [1 ]
Xue, J. Q. [3 ,4 ]
机构：
[1] Beijing Union Univ, Biochem Engn Coll, Beijing, Peoples R China
[2] Beijing Key Lab Biomass Waste Resource Utilizat, Beijing, Peoples R China
[3] Chinese Acad Sci, Inst High Energy Phys, Div Nucl Technol & Applicat, Beijing, Peoples R China
[4] Beijing Engn Res Ctr Radiog Tech & Equipment, Beijing, Peoples R China
来源：
BULGARIAN CHEMICAL COMMUNICATIONS | 2017年 / 49卷 / 04期
基金：
中国国家自然科学基金;
关键词：
matrix-assisted laser ionization; clenbuterol; matrix; sensitivity; MICROORGANISMS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF-MS) was used to analyze macromolecular compounds. The present study focused on how to use MALDI for determination of small molecules such as clenbuterol, and how to explore the matrix to improve the sensitivity. The macromolecular 1,2, 3,4-tetrakis(3',4'-hydroxyphenyl) thiophene matrix not only absorbed the laser energy but also caused sample desorption ionization. At the same time, it did not produce interfering ions of low molecular weight. Moreover, when perfluoro C-60 was added to the matrix, sensitivity was improved.
引用
收藏
页码：955 / 960
页数：6
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