Regulatory T cells and the pursuit of self-tolerance

被引：0
|
作者：
Hess, Allan D. [1 ]
机构：
[1] Johns Hopkins Univ, Baltimore, MD 21218 USA
来源：
BLOOD | 2007年 / 110卷 / 10期
关键词：
D O I：
10.1182/blood-2007-08-107920
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Failure of the CD4+CD25+Foxp3+ regulatory T-cell compartment to control immune reactivity to self-antigens leads to the development of chronic graft-versus-host disease largely mediated by donor-derived helper T cells that secrete proinflammatory cytokines.
引用
收藏
页码：3497 / 3498
页数：2
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