Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis; Evidence from 1100 ERCP cases

Aim: Since post-ERCP pancreatitis (PEP) is considered the most common complication of ERCP, it has been the focus of research to explore its prevention. Identifying patients with high-risk factors for PEP is one of the most important aspects for PEP prevention. Patients with high-risk factors should be carefully evaluated and alternative treatment and diagnostic techniques may be preferred instead of ERCP. Our aim in this study is to determine the risk factors in patients who develop pancreatitis after endoscopic retrograde cholangiopancreatography procedure and to determine an early and appropriate diagnosis and treatment approach in these patients. Material and Method: 1100 ERCPs performed by a single operator were included in this study. Post-ERCP pancreatitis (PEP) developed in 222 patients after the procedure. ERCP indications, age, gender, clinical findings, comorbidities and imaging frequencies of the patients who developed PEP were recorded before and after the procedure. R esult: 20.1% of the patient who underwent ERCP developed PEP. It was found that comorbidity and stent placement increased the development of PEP in patients who underwent ERCP. It was found that performing ERCP with the pre-incision method reduces the rate of PEP development. It was found that ERCP indications had no effect on the development of PEP. It was found that the rate of hospitalization in the intensive care unit increased in patients who developed PEP. It was found that the rate of PEP development decreased as operator experience increased. Discussion: The risk of PEP is multifactorial, and the effects of some risk factors can be minimized or completely eliminated. Different patient-related risk factors can help predict PEP.