Omega 3 Fatty Acids and GPR120

被引：76

作者：

Oh, Da Young ^{[1
]}

Olefsky, Jerrold M. ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Med, Div Endocrinol & Metab, La Jolla, CA 92093 USA

来源：

CELL METABOLISM | 2012年 / 15卷 / 05期

关键词：

INSULIN-RESISTANCE; OBESITY; LINKING;

D O I：

10.1016/j.cmet.2012.04.009

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Human loss-of-function gene variants in GPR120 have recently been identified that confer increased risk for obesity and metabolic syndrome. In addition, GPR120 KO mice develop obesity, increased inflammation, and insulin resistance, consistent with a role for GPR120 signaling in the metabolic syndrome and diabetes mellitus.

引用

页码：564 / 565

页数：2

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