Scleredema diabeticorum

Scleredema of Buschke is a rare connective tissue disease with a poorly understood pathogenesis. Three types of scleredeconditions. Type 1 is usually secondary to a febrile infection, type 2 is mostly associated with paraproteinemia and type 3, usually named scleredema diabeticorum, has a strict association with Diabetes mellitus. A diffuse, non-pitting swelling and induration of the skin define this disease. The skin histology is characterized by a normal or slightly thinned epidermis, and the dermis containing a decreased number of elastic fibers and thick large swollen collagen bundles sepathe deep reticular dermis. In this report we present a 58-year-old man with scleredema various possible treatments.