IL-6 in pulmonary hypertension: why novel is not always best

被引：23
|
作者：
Toshner, Mark [1 ,2 ]
Rothman, Alexander M. K. [3 ,4 ]
机构：
[1] Royal Papworth Hosp, Cambridge, England
[2] Univ Cambridge, Dept Med, Cambridge, England
[3] Univ Sheffield, Sheffield, S Yorkshire, England
[4] Sheffield Teaching Hosp NHS Trust, Sheffield, S Yorkshire, England
来源：
EUROPEAN RESPIRATORY JOURNAL | 2020年 / 55卷 / 04期
基金：
英国惠康基金;
关键词：
INTERLEUKIN-1;
D O I：
10.1183/13993003.00314-2020
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Role of interleukin-6 (IL-6) in pathogenesis of pulmonary hypertension
    Mathew, R
    Huang, J
    Yuan, N
    Bronstein, N
    Beneck, D
    Gewitz, MH
    Ray, P
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (04) : 717 - 717
  • [2] Protective Role of IL-6 in Vascular Remodeling in Schistosoma Pulmonary Hypertension
    Graham, Brian B.
    Chabon, Jacob
    Kumar, Rahul
    Kolosionek, Ewa
    Gebreab, Liya
    Debella, Elias
    Edwards, Michael
    Diener, Katrina
    Shade, Ted
    Gao Bifeng
    Bandeira, Angela
    Butrous, Ghazwan
    Jones, Kenneth
    Geraci, Mark
    Tuder, Rubin M.
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2013, 49 (06) : 951 - 959
  • [3] Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
    Cai, Zongye
    Tian, Siyu
    Klein, Theo
    Tu, Ly
    Geenen, Laurie W.
    Koudstaal, Thomas
    van den Bosch, Annemien E.
    de Rijke, Yolanda B.
    Reiss, Irwin K. M.
    Boersma, Eric
    van der Ley, Claude
    Van Faassen, Martijn
    Kema, Ido
    Duncker, Dirk J.
    Boomars, Karin A.
    Tran-Lundmark, Karin
    Guignabert, Christophe
    Merkus, Daphne
    SCIENTIFIC REPORTS, 2022, 12 (01)
  • [4] Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
    Zongye Cai
    Siyu Tian
    Theo Klein
    Ly Tu
    Laurie W. Geenen
    Thomas Koudstaal
    Annemien E. van den Bosch
    Yolanda B. de Rijke
    Irwin K. M. Reiss
    Eric Boersma
    Claude van der Ley
    Martijn Van Faassen
    Ido Kema
    Dirk J. Duncker
    Karin A. Boomars
    Karin Tran-Lundmark
    Christophe Guignabert
    Daphne Merkus
    Scientific Reports, 12
  • [5] ROLE OF IL-6 IN THE DEVELOPMENT OF HYPERTENSION
    Alyavi, Anis
    Alyavi, Bakhromkhon
    Abdullaev, Akbar
    Uzokov, Jamol
    Payziev, Djamshid
    ATHEROSCLEROSIS, 2024, 399
  • [6] IL-6 receptor overexpression in pulmonary arterial smooth muscle cells in idiopathic pulmonary hypertension
    Tamura, Yuichi
    Phan, Carole
    Tu, Ly
    Thuillet, Raphael
    Le Hiress, Morane
    Huertas, Alice
    Fadel, Elie
    Simonneau, Gerald
    Humbert, Marc
    Guignabert, Christophe
    EUROPEAN RESPIRATORY JOURNAL, 2015, 46
  • [7] Pulmonary arterial hypertension related to HIV: Is inflammation related to IL-6 the cornerstone?
    Tcherakian, C.
    Rivaud, E.
    Catherinot, E.
    Zucman, D.
    Metivier, A. -C.
    Couderc, L. -J.
    REVUE DE PNEUMOLOGIE CLINIQUE, 2011, 67 (04) : 250 - 257
  • [8] Immunomodulation of IL-6 gene expression by thymulin in monocrotaline model of pulmonary hypertension
    Henriques-Coelho, Tiago
    Carvalho, Filipe L.
    Oliveira, Silvia M.
    Santos, Mario
    Roncon-Albuquerque, Roberto, Jr.
    CIRCULATION, 2006, 114 (18) : 130 - 130
  • [9] Classical IL-6 signaling: a promising therapeutic target for pulmonary arterial hypertension
    Pullamsetti, Soni Savai
    Seeger, Werner
    Savai, Rajkumar
    JOURNAL OF CLINICAL INVESTIGATION, 2018, 128 (05): : 1720 - 1723
  • [10] IgE promotes pulmonary hypertension through mast cell–derived IL-6 and IL-13
    Nature Cardiovascular Research, 2022, 1 : 609 - 610
12345