A convenient synthesis of some 3-alkylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones

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作者
Kahveci, B [1 ]
Bekircan, O
Serdar, M
Ikizler, AA
机构
[1] Karadeniz Tech Univ, Dept Chem, TR-53100 Rize, Turkey
[2] Karadeniz Tech Univ, Dept Chem, Giresun, Turkey
[3] Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of 3-arylidenamino-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-ones N were obtained from the reaction of 3-amino-4-phenyl-45-dihydro-1H-1,2,4-triazol-5-one IVa with certain aldehydes. Compounds V were hydrogenated with NaBH, in diglyme to afford 3-alkylamino-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-ones. VI. So, a general and convenient method was improved for the synthesis of type VI compounds. Eleven new and potential biologically active compounds were synthesized and characterized by elemental analyses, C-13-NMR, H-1-NMR, UV and IR spectra.
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页码:615 / 618
页数:4
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