Unraveling Intra-Tumor Heterogeneity in Colorectal Cancer Using Oncoproteomics in Patient-Derived Organoids

被引：0
|
作者：
Pfohl, Ulrike [1 ]
Herter, Patrick [2 ]
Bashir, Sanam [3 ]
Erdmann, Gerrit [4 ]
Gambara, Guido [5 ]
Haybaeck, Johannes [6 ]
Kuehn, Ralf [3 ]
Mamlouk, Soulafa [5 ]
Silvestri, Alessandra [7 ]
Templin, Markus [2 ]
Regenbrecht, Christian [7 ]
机构：
[1] Otto von Guericke Univ, Magdeburg, Germany
[2] Univ Tubingen, Nat & Med Sci Inst, Reutlingen, Germany
[3] Max Delbruck Ctr Mol Med, Berlin, Germany
[4] NMI TT Pharmaserv, Berlin, Germany
[5] Charite Univ Med Berlin, Charite Comprehens Canc Ctr, Berlin, Germany
[6] Univ Klinikum Magdeburg, Inst Pathol, Magdeburg, Germany
[7] Cellphenomics GmbH, Berlin, Germany
来源：
ONCOLOGY RESEARCH AND TREATMENT | 2020年 / 43卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
334
引用
收藏
页码：199 / 200
页数：2
相关论文
共 50 条
  • [1] Unravelling intra-tumor phenotypic heterogeneity in colorectal cancer organoids
    Fletcher, Sabrina J.
    Catalano, Irene
    Grassi, Elena
    Borgato, Sofia
    Peracino, Barbara
    Piretto, Elena
    Alessandri, Luca
    Calogero, Raffaele
    Primo, Luca
    Trusolino, Livio
    Bertotti, Andrea
    Puliafito, Alberto
    CANCER RESEARCH, 2024, 84 (06)
  • [2] Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity
    Bruna R. S. Correa
    Joanna Hu
    Luiz O. F. Penalva
    Richard Schlegel
    David L. Rimm
    Pedro A. F. Galante
    Seema Agarwal
    Scientific Reports, 8
  • [3] Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity
    Correa, Bruna R. S.
    Hu, Joanna
    Penalva, Luiz O. F.
    Schlegel, Richard
    Rimm, David L.
    Galante, Pedro A. F.
    Agarwal, Seema
    SCIENTIFIC REPORTS, 2018, 8
  • [4] Paired colorectal and pancreatic cancer patient-derived tumor and organoids biobank
    Wang, Juiling
    Ma, Wen-Hui
    Lo, Yun-Chi
    Hsieh, Hsiao-Chun
    Hsiao, Li-Ju
    Bau, Yu-Pin
    Yang, Nai-Chieh
    Tsai, Shaw-Jenq
    Shan, Yan-Shen
    Chen, Tzu-Yu
    Chen, Yu-Ling
    Chiang, Pei-Ju
    Chen, Tzu-Ling
    Chang, Hsiu-Ping
    Chin, Hsian-Jean
    CANCER RESEARCH, 2024, 84 (06)
  • [5] Patient-Derived Tumor Organoids: A Platform for Precision Therapy of Colorectal Cancer
    Li, Yiran
    Wu, Wei
    Yao, Jiaxin
    Wang, Suidong
    Wu, Xiufeng
    Yan, Jun
    CELL TRANSPLANTATION, 2025, 34
  • [6] Assessment of intra-tumor heterogeneity in the xenograft of breast cancer-derived organoids with metastatic potential
    Tsuchiya, Ai
    Kumegawa, Kohei
    Saeki, Sumito
    Otsuji, Kazutaka
    Yang, Liying
    Suzuka, Jun
    Miyata, Kenichi
    Takahashi, Yoko
    Noda, Tetsuo
    Ohno, Shinji
    Imoto, Shigeru
    Ueno, Takayuki
    Maruyama, Reo
    CANCER SCIENCE, 2024, 115 : 777 - 777
  • [7] Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
    Bruun, Jarle
    Kryeziu, Kushtrim
    Eide, Peter W.
    Moosavi, Seyed H.
    Eilertsen, Ina A.
    Langerud, Jonas
    Rosok, Bard
    Totland, Max Z.
    Brunsell, Tuva H.
    Pellinen, Teijo
    Saarela, Jani
    Bergsland, Christian H.
    Palmer, Hector G.
    Brudvik, Kristoffer W.
    Guren, Tormod
    Dienstmann, Rodrigo
    Guren, Marianne G.
    Nesbakken, Arild
    Bjornbeth, Bjorn Atle
    Sveen, Anita
    Lothe, Ragnhild A.
    CLINICAL CANCER RESEARCH, 2020, 26 (15) : 4107 - 4119
  • [8] MODELING THE TUMOR MICROENVIRONMENT OF EARLY AND LATE ONSET COLORECTAL CANCER USING PATIENT-DERIVED ORGANOIDS
    Cohen, David
    Shin, Alice E.
    De, Dechokyab
    Mitani, Yosuke
    Li, Tianxia
    Rustgi, Anil K.
    Pumpalova, Yoanna S.
    Dionigi, Beatrice
    Gabre, Joel T.
    GASTROENTEROLOGY, 2024, 166 (05) : S47 - S48
  • [9] Advancements in Research and Treatment Applications of Patient-Derived Tumor Organoids in Colorectal Cancer
    van der Graaff, Denise
    Seghers, Sofie
    Vanclooster, Pieterjan
    Deben, Christophe
    Vandamme, Timon
    Prenen, Hans
    CANCERS, 2024, 16 (15)
  • [10] Patient-Derived Organoids from Colorectal Cancer with Paired Liver Metastasis Reveal Tumor Heterogeneity and Predict Response to Chemotherapy
    Mo, Shaobo
    Tang, Peiyuan
    Luo, Wenqin
    Zhang, Long
    Li, Yaqi
    Hu, Xiang
    Ma, Xiaoji
    Chen, Yikuan
    Bao, Yichao
    He, Xingfeng
    Fu, Guoxiang
    Xu, Xiaoya
    Rao, Xinxin
    Li, Xiaomeng
    Guan, Ruoyu
    Chen, Shengzhi
    Deng, Yun
    Lv, Tao
    Mu, Peiyuan
    Zheng, Qiang
    Wang, Simin
    Liu, Fangqi
    Li, Yiwei
    Sheng, Weiqi
    Huang, Dan
    Hu, Chen
    Gao, Jianjun
    Zhang, Zhen
    Cai, Sanjun
    Clevers, Hans
    Peng, Junjie
    Hua, Guoqiang
    ADVANCED SCIENCE, 2022, 9 (31)
12345