Milliseconds mixing in microfluidic channel using focused surface acoustic wave

被引:60
|
作者
Zeng, Q. [1 ,2 ]
Guo, F. [1 ,2 ]
Yao, L. [1 ,2 ]
Zhu, H. W. [1 ,2 ]
Zheng, L. [1 ,2 ]
Guo, Z. X. [1 ,2 ]
Liu, W. [1 ,2 ]
Chen, Y. [3 ]
Guo, S. S. [1 ,2 ]
Zhao, X. Z. [1 ,2 ]
机构
[1] Wuhan Univ, Minist Educ, Key Lab Artificial Micro & Nanostruct, Wuhan 430072, Peoples R China
[2] Wuhan Univ, Sch Phys & Technol, Wuhan 430072, Peoples R China
[3] Ecole Normale Super, Dept Chem, F-75231 Paris, France
来源
SENSORS AND ACTUATORS B-CHEMICAL | 2011年 / 160卷 / 01期
基金
中国国家自然科学基金;
关键词
Microfluidic; Focused surface acoustic wave; Mixing; IDTs;
D O I
10.1016/j.snb.2011.08.075
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A feasible approach of acoustic wave based ultra-fast homogeneous mixing in microfluidic channel is reported. After comparing simulation models of energy distribution between parallel interdigital transducers (IDTs) and concentric circular type focused interdigital transducers (F-IDTs), the F-IDTs were designed and built into microfluidic device to generate focused surface acoustic wave in a specific region of the microchannel. In the acoustic enhanced mixing region, continuous laminar flow was mixed efficiently in milliseconds by concentrated acoustic radiation. The active enhanced ultra-fast mixing was optimized and analyzed experimentally. This method could be developed for fast chemical or biochemical reactions and assays. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:1552 / 1556
页数:5
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