New t(11;12)(q12;q11) characterized by RxFISH in a patient with T-cell large granular lymphocyte leukemia

被引:2
|
作者
Salido, M [1 ]
Solé, F
Espinet, B
Zamora, L
Woessner, S
Florensa, L
机构
[1] Hosp del Mar, Lab Citol Hematol, Unitat Hematol 1973, IMAS,IMIM, Barcelona, Spain
[2] Hosp del Mar, Lab Reference Catalyuna, Unitat Hematol 1973, IMAS,IMIM, Barcelona, Spain
[3] Hosp del Mar, Ecola Citol Hematol S Woessner, IMAS, Unitat Hematol 1973,IMIM, Barcelona, Spain
关键词
D O I
10.1016/S0165-4608(00)00357-5
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Chromosomal abnormalities in patients with large granular lymphocyte leukemia (LGLL) are rare. Herein we present a novel cytogenetic abnormality t(11;12)(q12;q11) in a patient with LGLL identified by cross-species color banding (RxFISH). The application of RxFISH allowed the rapid and easy identification of a chromosome rearrangement that was not recognized by conventional cytogenetics. Therefore, RxFISH is a suitable complement to, but not a replacement for, conventional cytogenetics. (C) 2001 Elsevier Science Inc. All rights reserved.
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页码:70 / 73
页数:4
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