Identification and characterization of UBXD1, a novel UBX domain-containing gene on human chromosome 19p13, and its mouse ortholog

被引：14

作者：

Carim-Todd, L ^{[1
]}

Escarceller, M ^{[1
]}

Estivill, X ^{[1
]}

Sumoy, L ^{[1
]}

机构：

[1] Hosp Duran & Reynals, Inst Recerca Oncol, Med & Mol Genet Ctr, Barcelona 08907, Spain

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2001年 / 1517卷 / 02期

关键词：

UBXD1; UBX domain; EUROIMAGE; ubiquitin; cDNA sequencing;

D O I：

10.1016/S0167-4781(00)00248-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified a novel human gene, UBXD1, on chromosome 19p13, which encodes a putative protein containing a UBX domain. Expression analysis showed an enhanced presence in testis. We identified the corresponding orthologous genes in mouse and rat. The characterization of UBXD1 has allowed us to define a new class of UBX domain-containing proteins conserved during evolution. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：298 / 301

页数：4

共 20 条

[1] The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97
Trusch, Franziska
Matena, Anja
Vuk, Maja
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Freemont, Paul S.
Meyer, Hemmo
Bayer, Peter
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (49) : 29414 - 29427
[2] EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia
So, CW
Caldas, C
Liu, MM
Chen, SJ
Huang, QH
Gu, LJ
Sham, MH
Wiedemann, LM
Chan, LC
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (06) : 2563 - 2568
[3] Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13
Jang, WH
Weber, JS
Bashir, R
Bushby, K
Meisler, MH
GENOMICS, 1996, 36 (02) : 366 - 368
[4] Identification and characterization of BTBD1, a novel BTB domain containing gene on human chromosome 15q24
Carim-Todd, L
Sumoy, L
Andreu, N
Estivill, X
Escarceller, M
GENE, 2001, 262 (1-2) : 275 - 281
[5] Characterization of ZNF333, a novel double KRAB domain containing zinc finger gene on human chromosome 19p13.1
Tian, Y
Breedveld, GJ
Huang, SZ
Oostra, BA
Heutink, P
Lo, WHY
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 2002, 1577 (01): : 121 - 125
[6] The human PIN1 peptidyl-prolyl cis/trans isomerase gene maps to human chromosome 19p13 and the closely related PIN1L gene to 1p31
Campbell, HD
Webb, GC
Fountain, S
Young, IG
GENOMICS, 1997, 44 (02) : 157 - 162
[7] IDENTIFICATION OF A NEW MURINE RUNT DOMAIN-CONTAINING GENE, CBFA3, AND LOCALIZATION OF THE HUMAN HOMOLOG, CBFA3, TO CHROMOSOME 1P35-PTER
WIJMENGA, C
SPECK, NA
DRACOPOLI, NC
HOFKER, MH
LIU, P
COLLINS, FS
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[8] Assignment of PDZ domain-containing protein GIPC gene (C19orf3) to human chromosome band 19p13.1 by in situ hybridization and radiation hybrid mapping
Von Kap-Herr, C
Kandala, G
Mann, SS
Hart, TC
Pettenati, MJ
Setaluri, V
CYTOGENETICS AND CELL GENETICS, 2000, 89 (3-4): : 234 - 235
[9] A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes the candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors
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Wen Ouyang
Shaojian Lin
Aining Xu
Yuanliang Zhang
Yinyin Xie
Qiuhua Huang
Weili Zhao
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Saijuan Chen
Jinyan Huang
Zhe Bao Wu
Xiaojian Sun
Frontiers of Medicine, 2023, 17 : 458 - 475
[10] A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes the candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors
Liu, Dan
Xu, Chunhui
Liu, Yanting
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Lin, Shaojian
Xu, Aining
Zhang, Yuanliang
Xie, Yinyin
Huang, Qiuhua
Zhao, Weili
Chen, Zhu
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Huang, Jinyan
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FRONTIERS OF MEDICINE, 2023, 17 (03) : 458 - 475

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