Fulminating septicemia due to persistent pan-resistant community-acquired metallo-β-lactamase (IMP-1)-positive Acinetobacter baumannii

被引：8
|
作者：
Telang, Nilima V. [2 ]
Satpute, Meenakshi G. [2 ]
Dhakephalkar, Prashant K. [3 ]
Niphadkar, Krishna B. [2 ]
Joshi, Suresh G. [1 ]
机构：
[1] Drexel Univ, Coll Med, Philadelphia, PA 19102 USA
[2] Univ Pune Affiliate, Interdisciplinary Sch Biomed Sci, King Edward Mem Hosp, Dept Microbiol, Pune, Maharashtra, India
[3] Agharkar Res Inst, DNA Sequencing Lab, Pune, Maharashtra, India
来源：
INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY | 2011年 / 54卷 / 01期
关键词：
Acinetobacter baumannii; carbapenemase extended spectrum beta lactamase; IMP; metallo-beta-lactamase; nosocomial infection; pan-resistant; septicemia;
D O I：
10.4103/0377-4929.77397
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Acinetobacter baumannii is considered as an emerging nosocomial pathogen and is renowned for its multi-drug resistance. We report a case of community-acquired pan-resistant A. baumannii caused fulminating septicemia. The treatment failure led to death. The A. baumannii strain isolated from blood, pus, urine and tracheal aspirate was confirmed by 16S r-RNA sequence homology and found positive for metallo-beta-lactamase IMP-1, and was found to be a strong biofilm producer. The isolate was only susceptible (moderately) to colistin.
引用
收藏
页码：180 / 182
页数：3
相关论文
共 11 条
  • [1] Dissemination of IMP-1 metallo-β-lactamase-producing Acinetobacter species in a Brazilian teaching hospital
    Tognim, Maria C. B.
    Gales, Ana C.
    Penteado, Andreia P.
    Silbert, Suzane
    Sader, Helio S.
    INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2006, 27 (07): : 742 - 747
  • [2] Dissemination of IMP-1 and OXA type β-lactamase in carbapenem-resistant Acinetobacter baumannii
    Sung, Ji Youn
    Kwon, Kye Chul
    Park, Jong Woo
    Kim, Yeon Suk
    Kim, Ji Myung
    Shin, Kyeong Seob
    Kim, Jong Wan
    Ko, Chi Seon
    Shin, So Youn
    Song, Jeong Hoon
    Koo, Sun Hoe
    KOREAN JOURNAL OF LABORATORY MEDICINE, 2008, 28 (01): : 16 - 23
  • [3] Identification and characterization of IMP-1 metallo-β-lactamase producing Acinetobacter species from non-tertiary hospitals
    Kim, S.
    Cha, J. O.
    Kim, I. H.
    Kim, H. S.
    Park, C.
    Yu, J-Y.
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2015, 45 : S71 - S71
  • [4] Analysis of IMP-1 type metallo-β-lactamase-producing Acinetobacter radioresistens isolated from companion animals
    Kimura, Yui
    Miyamoto, Tadashi
    Aoki, Kotaro
    Ishii, Yoshikazu
    Harada, Kazuki
    Watarai, Masahisa
    Hatoya, Shingo
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 2017, 23 (09) : 655 - 657
  • [5] False-positive results in screening for metallo-β-lactamase are observed in isolates of Acinetobacter baumannii due to production of oxacilinases
    Martins, Andreza F.
    Borges, Aline
    Pagano, Mariana
    Dalla-Costa, Libera Maria
    Barth, Afonso L.
    BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, 2013, 17 (04): : 500 - 501
  • [6] Crystal Structure of IMP-2 Metallo-β-lactamase from Acinetobacter spp.: Comparison of Active-Site Loop Structures between IMP-1 and IMP-2
    Yamaguchi, Yoshihiro
    Matsueda, Satoshi
    Matsunaga, Kazuyo
    Takashio, Nobutoshi
    Toma-Fukai, Sachiko
    Yamagata, Yuriko
    Shibata, Naohiro
    Wachino, Jun-ichi
    Shibayama, Keigo
    Arakawa, Yoshichika
    Kurosaki, Hiromasa
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2015, 38 (01) : 96 - 101
  • [7] Detection of plasmid-mediated IMP-1 metallo-β-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
    Li-rong Chen
    Hong-wei Zhou
    Jia-chang Cai
    Rong Zhang
    Gong-xiang Chen
    Journal of Zhejiang University SCIENCE B, 2009, 10 : 348 - 354
  • [8] Detection of plasmid-mediated IMP-1 metallo-β-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
    Lirong CHENHongwei ZHOUJiachang CAIRong ZHANGGongxiang CHENClinical Laboratory Centerthe Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou ChinaCancer InstituteZhejiang UniversityHangzhou China
    Journal of Zhejiang University(Science B:An International Biomedicine & Biotechnology Journal), 2009, (05) : 348 - 354
  • [9] Detection of plasmid-mediated IMP-1 metallo-β-lactamase and quinolone resistance determinants in an ertapenem-resistant Enterobacter cloacae isolate
    Chen, Li-rong
    Zhou, Hong-wei
    Cai, Jia-chang
    Zhang, Rong
    Chen, Gong-xiang
    JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2009, 10 (05): : 348 - 354
  • [10] Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea
    Lee, K
    Yum, JH
    Yong, DG
    Lee, HM
    Kim, HD
    Docquier, JD
    Rossolini, GM
    Chong, YS
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (11) : 4485 - 4491
12