The synthesis of pennogenin 3-O-β-D-glucopyranosyl-(1 → 3)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-glucopyranoside

被引：6

作者：

Luo, Xin-Feng ^{[1
]}

Lei, Fan ^{[1
]}

He, Yi ^{[1
]}

Pei, Shu-Chen ^{[1
]}

Hai, Li ^{[1
]}

Qian, Shan ^{[2
]}

Wu, Yong ^{[1
]}

机构：

[1] Sichuan Univ, W China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist, Chengdu 610041, Peoples R China

[2] Xihua Univ, Bioengn Coll, Chengdu 610039, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2012年 / 14卷 / 04期

关键词：

pennogenin; alpha-L-rhamnopyranoside; beta-D-glucopyranoside; antitumor activity; synthesis; GRACILLIN; SAPONINS; GLYCOSYL;

D O I：

10.1080/10286020.2011.653348

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Pennogenin 3-O-beta-D-glucopyranosyl-(1 -> 3)-[alpha-L-rhamnopyranosyl-(1 -> 2)]-beta-D-glucopyranoside, a monodesmosidic saponin isolated from Paris polyphylla Smith var. yunnanensis with promised antitumor activities, was firstly synthesized from glucoside thiol via nine steps and with 27% overall yield.

引用

页码：314 / 321

页数：8

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