In Vitro Activity of Thimerosal against Ocular Pathogenic Fungi

被引：13
|
作者：
Xu, Yan [1 ]
Pang, Guangren [1 ]
Zhao, Dongqing [1 ]
Gao, Chuanwen [1 ]
Zhou, Lutan [1 ]
Sun, Shengtao [1 ]
Wang, Bingliang [2 ]
机构：
[1] Henan Prov Peoples Hosp, Dept Ophthalmol, Henan Eye Inst, Zhengzhou, Peoples R China
[2] Anyang Eye Hosp, Anyang, Peoples R China
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 01期
关键词：
ANTIFUNGAL SUSCEPTIBILITY; KERATITIS; SPECTRUM; PRESERVATIVES; FUSARIUM; CHINA;
D O I：
10.1128/AAC.00714-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The in vitro activity of thimerosal versus those of amphotericin B and natamycin was assessed against 244 ocular fungal isolates. The activity of thimerosal against Fusarium spp., Aspergillus spp., and Alternaria alternata was 256 times, 512 times, and 128 times, respectively, greater than that of natamycin and 64 times, 32 times, and 32 times, respectively, greater than that of amphotericin B. Thimerosal's antifungal activity was significantly superior to those of amphotericin B and natamycin against ocular pathogenic fungi in vitro.
引用
收藏
页码：536 / 539
页数：4
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