Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

被引:2
|
作者
Stavtsev, Dmitry D. [1 ]
Volkov, Mikhail V. [2 ]
Margaryants, Nikita B. [2 ]
Potemkin, Andrey, V [2 ]
Dremin, Viktor V. [1 ]
Kozlov, Igor O. [1 ]
Makovik, Irina N. [1 ]
Zherebtsov, Evgeny A. [3 ]
Dunaev, Andrey, V [1 ]
机构
[1] Orel State Univ, Res & Dev Ctr Biomed Photon, Oryol 302020, Russia
[2] ITMO Univ, St Petersburg 197101, Russia
[3] Univ Oulu, OPEM, Oulu 90014, Finland
基金
俄罗斯科学基金会;
关键词
videocapillaroscopy; laser Doppler flowmetry; velocity of capillary blood flow; microcirculation; rheumatic diseases; cold pressor test; RAYNAUDS-PHENOMENON;
D O I
10.1117/12.2523190
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.
引用
收藏
页数:6
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