Ising-model description of long-range correlations in DNA sequences

被引：16
|
作者：
Colliva, A. [1 ,2 ]
Pellegrini, R. [3 ]
Testori, A. [1 ,2 ]
Caselle, M. [1 ,2 ]
机构：
[1] Univ Turin, Dipartimento Fis, I-10125 Turin, Italy
[2] Ist Nazl Fis Nucl, Sez Torino, I-10125 Turin, Italy
[3] Swansea Univ, Dept Phys, Swansea SA2 8PP, W Glam, Wales
来源：
PHYSICAL REVIEW E | 2015年 / 91卷 / 05期
关键词：
DISTRIBUTIONS;
D O I：
10.1103/PhysRevE.91.052703
中图分类号：
O35 [流体力学]; O53 [等离子体物理学];
学科分类号：
070204 ; 080103 ; 080704 ;
摘要：
We model long-range correlations of nucleotides in the human DNA sequence using the long-range one-dimensional (1D) Ising model. We show that, for distances between 10(3) and 10(6) bp, the correlations show a universal behavior and may be described by the non-mean-field limit of the long-range 1D Ising model. This allows us to make some testable hypothesis on the nature of the interaction between distant portions of the DNA chain which led to the DNA structure that we observe today in higher eukaryotes.
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页数：8
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