Synthesis of some novel functionalized dihydropyrido[2,3-d]pyrimidines via an one-pot three-component reaction catalysed by InCl3

被引:28
|
作者
Naidu, P. Seetham [1 ]
Borah, Pallabi [1 ]
Bhuyan, Pulak J. [1 ]
机构
[1] CSIR NE Inst Sci & Technol, Div Med Chem, Jorhat 785006, Assam, India
关键词
Dihydropyridine; Pyrimidine; Indole; Multi-component reactions (MCRs); Indium chloride; THIOPYRANO INDOLE-DERIVATIVES; POLYHYDROQUINOLINE DERIVATIVES; SIMPLE OXINDOLE; FACILE; ANALOGS; COMPLEX;
D O I
10.1016/j.tetlet.2012.05.102
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Some novel functionalized dihydropyrido[2,3-d]pyrimidine derivatives 4 were synthesized using a one-pot three-component reaction of 6-aminouracils 1, aryl aldehydes 2 and 3-cyanoacetyl indole 3 using InCl3 as catalyst. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4015 / 4017
页数:3
相关论文
共 50 条
  • [1] ONE-POT AND THREE-COMPONENT SYNTHESIS OF SOME NOVEL FUNCTIONALIZED CHROMONYL PYRIDO[2,3-d]PYRIMIDINES AS ANTICANCER AGENTS
    Ali, Tarik E.
    Assiri, Mohammed A.
    Shati, Ali A.
    Alfaifi, Mohammad Y.
    Elbehairi, Serag Eldin, I
    El-Kott, Attalla F.
    HETEROCYCLES, 2021, 102 (05) : 930 - 940
  • [2] One-pot synthesis of pyrido[2,3-d]pyrimidines via efficient three-component reaction in aqueous media
    Shi, Daqing
    Niu, Liliui
    Shi, Jingwen
    Wang, Xiangshan
    Ji, Shunjun
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 44 (05) : 1083 - 1090
  • [3] One-pot Three-component Reaction of Barbituric acids, Aldehydes and 4-Hydroxycoumarins: Synthesis of Some Novel Functionalized Furo[2,3-d]pyrimidines
    Dutta, Leema
    Bhuyan, Pulak J.
    CHEMISTRYSELECT, 2016, 1 (18): : 5944 - 5947
  • [4] A novel three-component one-pot synthesis of pyrano[2,3-d]pyrimidines and pyrido[2,3-d]pyrimidines using microwave heating in the solid state
    Devi, I
    Kumar, BSD
    Bhuyan, PJ
    TETRAHEDRON LETTERS, 2003, 44 (45) : 8307 - 8310
  • [5] A novel one-pot three-component reaction for the synthesis of 5-arylamino-pyrrolo[2,3-d]pyrimidines under microwave irradiation
    Naidu, P. Seetham
    Bhuyan, Pulak J.
    RSC ADVANCES, 2014, 4 (20) : 9942 - 9945
  • [6] Novel One-Pot Three-Component Reaction for the Synthesis of Functionalized Spiroquinazolinones
    Tajbakhsh, Mahdieh
    Ramezanpour, Sorour
    Balalaie, Saeed
    Bijanzadeh, Hamid Reza
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 52 (05) : 1559 - 1564
  • [7] Synthesis of novel oxindolylpyrrolo[2,3-d]pyrimidines via a three-component sequential tandem reaction
    Rad-Moghadam, Kurosh
    Azimi, Seyyedeh Cobra
    TETRAHEDRON, 2012, 68 (47) : 9706 - 9712
  • [8] Using Kiwi Juice as a Green Biocatalyst for the Synthesis of Pyrano[2,3-d]pyrimidines in the Facile One-pot, Three-Component Reaction
    Tata, Mohsen
    Marandi, Ghasem
    Marjani, Ahmad Poursattar
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2023, 13 (01):
  • [9] Regioisomeric synthesis of dihydrofuro[2,3-d]pyrimidines in a diastereoselective manner involving nitrogen ylides in one-pot three-component reaction
    Dutta, Leema
    Sharma, Meenakshi
    Bhuyan, Pulak J.
    TETRAHEDRON, 2016, 72 (42) : 6654 - 6660
  • [10] One-pot, three-component Synthesis of pyrrolo[2,3-d]pyrimidine Derivatives
    Javahershenas, Ramin
    Khalafy, Jabbar
    JOURNAL OF THE MEXICAN CHEMICAL SOCIETY, 2018, 62 (01)