Investigation of two-way fluid-structure interaction of blood flow in a patient-specific left coronary artery

被引:15
|
作者
Athani, Abdulgaphur [1 ]
Ghazali, Nik Nazri Nik [1 ]
Badruddin, Irfan Anjum [2 ,3 ]
Kamangar, Sarfaraz [3 ]
Anqi, Ali E. [3 ]
Algahtani, Ali [2 ,3 ]
机构
[1] Univ Malaya, Fac Engn, Dept Mech Engn, Kuala Lumpur, Malaysia
[2] King Khalid Univ, Res Ctr Adv Mat Sci RCAMS, Abha, Asir, Saudi Arabia
[3] King Khalid Univ, Coll Engn, Mech Engn Dept, Abha, Asir, Saudi Arabia
关键词
Left coronary artery; image processing; CFD; FSI; blood flow modeling; SHEAR-STRESS; HEMODYNAMIC PARAMETERS; NUMERICAL-ANALYSIS; WALL; BIFURCATION; STENOSIS; ATHEROSCLEROSIS; THICKNESS; PLAQUE;
D O I
10.3233/BME-201171
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
BACKGROUND: The blood flow in the human artery has been a subject of sincere interest due to its prime importance linked with human health. The hemodynamic study has revealed an essential aspect of blood flow that eventually proved to be paramount to make a correct decision to treat patients suffering from cardiac disease. OBJECTIVE: The current study aims to elucidate the two-way fluid-structure interaction (FSI) analysis of the blood flow and the effect of stenosis on hemodynamic parameters. METHODS: A patient-specific 3D model of the left coronary artery was constructed based on computed tomography (CT) images. The blood is assumed to be incompressible, homogenous, and behaves as Non-Newtonian, while the artery is considered as a nonlinear elastic, anisotropic, and incompressible material. Pulsatile flow conditions were applied at the boundary. Two-way coupled FSI modeling approach was used between fluid and solid domain. The hemodynamic parameters such as the pressure, velocity streamline, and wall shear stress were analyzed in the fluid domain and the solid domain deformation. RESULTS: The simulated results reveal that pressure drop exists in the vicinity of stenosis and a recirculation region after the stenosis. It was noted that stenosis leads to high wall stress. The results also demonstrate an overestimation of wall shear stress and velocity in the rigid wall CFD model compared to the FSI model.
引用
收藏
页码:13 / 30
页数:18
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