Somatostatin Imaging of Neuroendocrine-Differentiated Prostate Cancer

被引：1
|
作者：
Hope, Thomas A. [1 ]
Aggarwal, Rahul [2 ]
Simko, Jeff P. [3 ,4 ,5 ]
VanBrocklin, Henry F. [1 ]
Ryan, Charles J. [2 ]
机构：
[1] Univ Calif San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Div Hematol Oncol, Dept Med, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, Dept Urol, San Francisco, CA 94143 USA
[5] Univ Calif San Francisco, Dept Radiat Oncol, San Francisco, CA 94143 USA
来源：
CLINICAL NUCLEAR MEDICINE | 2015年 / 40卷 / 06期
关键词：
prostate cancer; octreotide; neuroendocrine; somatostatin; FDG;
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
After prolonged androgen deprivation therapy, a subset of castrate-resistant prostate cancer patients will develop neuroendocrine prostate cancer (NEPC) associated with resistance to further hormonal therapy and frequent visceral metastases. Imaging the presence of somatostatin receptors on the cancer cell surface may provide a readily available, noninvasive means to distinguish adenocarcinoma from NEPC. This distinction is important for therapeutic decision making and may open the door for developing novel radionuclide targets for the treatment of this aggressive subtype of prostate cancer. We describe a case of NEPC successfully imaged using In-111-labeled octreotide.
引用
收藏
页码：540 / 541
页数：2
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