Intratumoral injection of IL-12 and TNFα loaded poly-lactic acid microspheres leads to regression of primary breast cancer and systemic anti-tumor immunity

被引：0
|
作者：
Sabel, MS
Woolson, D
Bailey, NA
Egilmez, NK
Mathiowitz, E
Chang, AE
机构：
[1] Univ Michigan, Ann Arbor, MI 48109 USA
[2] Brown Univ, Providence, RI 02912 USA
[3] SUNY Buffalo, Buffalo, NY 14260 USA
来源：
ANNALS OF SURGICAL ONCOLOGY | 2003年 / 10卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
14
引用
收藏
页码：S12 / S12
页数：1
相关论文
共 32 条
  • [1] Intratumoral IL-12 and TNF-α-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity
    Sabel, MS
    Skitzki, J
    Stoolman, L
    Egilmez, NK
    Mathiowitz, E
    Bailey, N
    Chang, WJ
    Chang, AE
    ANNALS OF SURGICAL ONCOLOGY, 2004, 11 (02) : 147 - 156
  • [2] Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity
    Michael S. Sabel
    Joseph Skitzki
    Lloyd Stoolman
    Nejat K. Egilmez
    Edith Mathiowitz
    Nicola Bailey
    Wen-Jian Chang
    Alfred E. Chang
    Annals of Surgical Oncology, 2004, 11 : 147 - 156
  • [3] Intralesional IL-12 and TNF-α loaded microspheres can generate systemic anti-tumor immunity to B16 melanoma
    M. S. Sabel
    W. J. Chang
    N. K. Egilmez
    E. Mathiowitz
    A. E. Chang
    Annals of Surgical Oncology, 2004, 11 : S87 - S87
  • [4] Intralesional IL-12 and TNF-α loaded microspheres can generate systemic anti-tumor immunity to B16 melanoma
    Sabel, MS
    Chang, WJ
    Egilmez, NK
    Mathiowitz, E
    Chang, AE
    ANNALS OF SURGICAL ONCOLOGY, 2004, 11 (02) : S87 - S87
  • [5] Synergistic effect of intratumoral IL-12 and TNF-α microspheres:: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells
    Sabel, Michael S.
    Arora, Alisha
    Su, Gang
    Mathiowitz, Edith
    Reineke, Joshua J.
    Chang, Alfred E.
    SURGERY, 2007, 142 (05) : 749 - 760
  • [6] Generation of a tumor-specific systemic response after intratumoral injection of IL-12 and IL-18-loaded polylactic acid microspheres
    Sabel, Michael S.
    Arora, Alisha
    Su, Gang
    Griffith, Kent A.
    Mathiowitz, Edith
    Reineke, Joshua J.
    Chang, Alfred E.
    JOURNAL OF IMMUNOTHERAPY, 2007, 30 (08) : 808 - 816
  • [7] Intratumoral delivery of a P2A-linked bicistronic IL-12 construct leads to high intratumoral expression and systemic anti-tumor response
    Canton, David A.
    Burkart, Christoph
    Shirley, Shawna A.
    Mukhopadhyay, Anandaroop
    Connolly, Richard J.
    Bahrami, Arya
    Campbell, Jean S.
    Pierce, Robert H.
    CANCER RESEARCH, 2017, 77
  • [8] Intratumoral plasmid IL-12 enhanced the systemic anti-tumor effect of anti-PD-1 antibody in triple-negative breast cancer.
    Nagata, Hiroshi
    Osada, Takuya
    Crosby, Erika J.
    Canton, David A.
    Twitty, Chris G.
    Lyerly, H. Kim
    CANCER RESEARCH, 2021, 81 (13)
  • [9] Neoadjuvant intratumoral cytokine-loaded microspheres are superior to postoperative autologous cellular vaccines in generating systemic anti-tumor immunity
    Arora, Alisha
    Su, Gang
    Mathiowitz, Edith
    Reineke, Joshua
    Chang, Alfred E.
    Sabel, Michael S.
    JOURNAL OF SURGICAL ONCOLOGY, 2006, 94 (05) : 403 - 412
  • [10] Activation of systemic anti-tumor immunity by in situ ablation of breast carcinoma by intratumoral 224Ra-loaded wires
    Confino, H.
    Hochman, I.
    Efrati, M.
    Schmidt, M.
    Umansky, V.
    Kelson, I.
    Keisari, Y.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S213 - S213
1234