Rapid Proliferation Compensates for Defective Filamentation in Candida albicans Pathogenesis

被引：0

作者：

Kadosh, David ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Microbiol Immunol & Mol Genet, 7703 Floyd Curl Dr,MC 7758, San Antonio, TX 78229 USA

来源：

TRENDS IN MICROBIOLOGY | 2021年 / 29卷 / 10期

基金：

美国国家卫生研究院;

关键词：

BLOOD-STREAM INFECTIONS; MORPHOLOGY; HOSPITALS;

D O I：

10.1016/j.tim.2021.08.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A recent study (Dunker et al.) has shown that a Candida albicans mutant, defective for filamentation, is fully virulent due to rapid cellular proliferation in host tissues. These findings challenge the current paradigm in C. albicans pathogenesis and suggest that defects in one virulence property can be compensated for by enhancements in another.

引用

页码：867 / 868

页数：2

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