Optimal linkage disequilibrium splitting

被引：8
|
作者：
Prive, Florian [1 ]
机构：
[1] Aarhus Univ, Natl Ctr Register Based Res, DK-8210 Aarhus, Denmark
来源：
BIOINFORMATICS | 2022年 / 38卷 / 01期
关键词：
D O I：
10.1093/bioinformatics/btab519
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Motivation: A few algorithms have been developed for splitting the genome in nearly independent blocks of linkage disequilibrium. Due to the complexity of this problem, these algorithms rely on heuristics, which makes them suboptimal. Results: Here, we develop an optimal solution for this problem using dynamic programming.
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页码：255 / 256
页数：2
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