Frequency of malignancy in lesions classified as probably benign after dynamic contrast-enhanced breast MRI examination

被引:45
|
作者
Sadowski, EA [1 ]
Kelcz, F [1 ]
机构
[1] Univ Wisconsin, Dept Radiol, Madison, WI 53792 USA
关键词
breast MRI; probably benign breast lesions; BI-RADS; 3; follow-up mammography; breast neoplasm;
D O I
10.1002/jmri.20312
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: To determine the chance of malignancy in lesions classified as "probably benign" by dynamic magnetic resonanec imaging (MRI), in a heterogeneous population. Materials and Methods: Reports from 473 patients. from March 1994 to March 2002, who underwent breast M were retrospectively reviewed. A total of 79 patients (17%) had lesions classified as probably benign after the MRI, which required further imaging follow-up. We evaluated subsequent MRI, mammographic reports, and clinical follow-up in these patients and established the frequency of malignancy in this group. Results: MRI classified probably benign lesion were diagnosed in 79 women because of focal or diffuse mild enhancement and benign dynamic enhancement curves in the area of the mammographic abnormality, or because of the presence of microcalcifications on the mammogram, or because of incidental enhancing lesions. Two-year radiographic and/or clinical follow-up was available in 68 women. On follow-up, four women (6%) were diagnosed with cancer between 14 and 18 months after the initial MRI. Conclusion: Patients with a lesion assessed as probably benign by dynamic contrast enhanced MRI have a higher chance of malignancy than patients with probably benign lesions (Breast Imaging Reporting and Data System category 3, BI-RADS 3) seen on mammography. These patients should be informed of the increased risk of cancer and be given the option of biopsy or close follow-up.
引用
收藏
页码:556 / 564
页数:9
相关论文
共 50 条
  • [1] Frequency of Malignancy Seen in Probably Benign Lesions at Contrast-enhanced Breast MR Imaging: Findings from ACRIN 6667
    Weinstein, Susan P.
    Hanna, Lucy G.
    Gatsonis, Constantine
    Schnall, Mitchell D.
    Rosen, Mark A.
    Lehman, Constance D.
    RADIOLOGY, 2010, 255 (03) : 731 - 737
  • [2] The Frequency and Causes of Not-Detected Breast Malignancy in Dynamic Contrast-Enhanced MRI
    Song, Donghun
    Kang, Bong Joo
    Kim, Sung Hun
    Lee, Jeongmin
    Park, Ga Eun
    DIAGNOSTICS, 2022, 12 (11)
  • [3] Probably Benign Breast MRI Lesions: Frequency, Lesion Type, and Rate of Malignancy
    Lourenco, Ana P.
    Chung, Michelle Tsang Mui
    Mainiero, Martha B.
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2014, 39 (04) : 789 - 794
  • [4] Frequency of Malignancy and Imaging Characteristics of Probably Benign Lesions Seen at Breast MRI
    Grimm, Lars J.
    Anderson, Andy L.
    Baker, Jay A.
    Johnson, Karen S.
    Walsh, Ruth
    Yoon, Sora C.
    Ghate, Sujata V.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2015, 205 (02) : 442 - 446
  • [5] Optimizing ultrafast dynamic contrast-enhanced MRI scan duration in the differentiation of benign and malignant breast lesions
    Cao, Ying
    Huang, Yao
    Chen, Xianglong
    Wang, Wei
    Chen, Huifang
    Yin, Ting
    Nickel, Dominik
    Li, Changchun
    Shao, Junhua
    Zhang, Shi
    Wang, Xiaoxia
    Zhang, Jiuquan
    INSIGHTS INTO IMAGING, 2024, 15 (01)
  • [6] Differentiation of malignant and benign breast lesions using magnetization transfer imaging and dynamic contrast-enhanced MRI
    Heller, Samantha L.
    Moy, Linda
    Lavianlivi, Sherlin
    Moccaldi, Melanie
    Kim, Sungheon
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2013, 37 (01) : 138 - 145
  • [7] Dynamic contrast-enhanced MRI of ocular lesions
    Heverhagen, JT
    von Tengg-Kobligk, H
    Baudendistel, KT
    Chun, H
    Jia, G
    Davidorf, FH
    Craig, EL
    Knopp, MV
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2004, 182 (04) : 31 - 31
  • [8] Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions?
    Rasha Mohamed Kamal
    Mennatallah Mohamed Hanafy
    Sahar Mahmoud Mansour
    Maher Hassan
    Mohamed Mohamed Gomaa
    Egyptian Journal of Radiology and Nuclear Medicine, 51
  • [9] Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions?
    Kamal, Rasha Mohamed
    Hanafy, Mennatallah Mohamed
    Mansour, Sahar Mahmoud
    Hassan, Maher
    Gomaa, Mohamed Mohamed
    EGYPTIAN JOURNAL OF RADIOLOGY AND NUCLEAR MEDICINE, 2020, 51 (01):
  • [10] Optimization of Time-to-peak Analysis for Differentiating Malignant and Benign Breast Lesions with Dynamic Contrast-Enhanced MRI
    Liu, Fang
    Kornecki, Anat
    Shmuilovich, Olga
    Gelman, Neil
    ACADEMIC RADIOLOGY, 2011, 18 (06) : 694 - 704