Combination of poly(L-lysine)-graft-dextran copolymer and 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) modification synergistically stabilizes pyrimidine motif triplex at neutral pH

被引：2

作者：

Torigoe, H

Katayama, T

Obika, S

Maruyama, A

Imanishi, T

机构：

[1] Tokyo Univ Sci, Dept Appl Chem, Fac Sci, Shinjuku Ku, Tokyo, Japan

[2] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka, Japan

[3] Kyushu Univ, Inst Mat Chem & Engn, Fukuoka 812, Japan

[4] PRESTO, Japan Sci & Technol Agcy, Kawaguchi, Japan

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2005年 / 24卷 / 5-7期

关键词：

PHYSIOLOGICAL PH; DNA FORMATION;

D O I：

10.1081/NCN-200060113

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：635 / 638

页数：4

共 13 条

[1] Promotion of triplex formation by 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) modification:: Thermodynamic and kinetic studies
Torigoe, H
Obika, S
Imanishi, T
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2001, 20 (4-7): : 1235 - 1238
[2] 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA):: Synthesis and triplex-forming properties
Obika, S
Uneda, T
Sugimoto, T
Nanbu, D
Minami, T
Doi, T
Imanishi, T
BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (04) : 1001 - 1011
[3] Poly(L-lysine)-graft-dextran copolymer promotes pyrimidine motif triplex DNA formation at physiological pH -: Thermodynamic and kinetic studies
Torigoe, H
Ferdous, A
Watanabe, H
Akaike, T
Maruyama, A
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (10) : 6161 - 6167
[4] Triplex-forming enhancement with high sequence selectivity by single 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) modification
Obika, S
Hari, Y
Sugimoto, T
Sekiguchi, M
Imanishi, T
TETRAHEDRON LETTERS, 2000, 41 (46) : 8923 - 8927
[5] Poly(L-lysine)-graft-dextran copolymer remarkably promotes pyrimidtne-motif triplex formation at neutral pH: Thermodynamic and kinetic studies
Torigoe, H
Ferdous, A
Watanabe, H
Akaike, T
Maruyama, A
NUCLEOSIDES & NUCLEOTIDES, 1999, 18 (6-7): : 1655 - 1656
[6] 2′-O,4′-C-methylene bridged nucleic acid modification promotes pyrimidine motif tripler DNA formation at physiological pH -: Thermodynamic and kinetic studies
Torigoe, H
Hari, Y
Sekiguchi, M
Obika, S
Imanishi, T
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (04) : 2354 - 2360
[7] Triplex formation involving 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) with 2-pyridone base analogue:: Efficient and selective recognition of C:G interruption
Torigoe, H
Hari, Y
Obika, S
Imanishi, T
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (5-8): : 1097 - 1099
[8] 2′-O,4′-C-Aminomethylene-Bridged Nucleic Acid Modification with Enhancement of Nuclease Resistance Promotes Pyrimidine Motif Triplex Nucleic Acid Formation at Physiological pH
Torigoe, Hidetaka
Rahman, S. M. Abdur
Takuma, Hiroko
Sato, Norihiro
Imanishi, Takeshi
Obika, Satoshi
Sasaki, Kiyomi
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (09) : 2742 - 2751
[9] Triplex formation involving 2′-O,4′-C-methylene bridged nucleic acid (2′,4′-BNA) with 1-isoquinolone base analogue:: Efficient and selective recognition of C:G interruption
Torigoe, H
Hari, Y
Obika, S
Imanishi, T
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (5-8): : 1571 - 1573
[10] 2'-O,4'-C-ethylene bridged nucleic acid modification enhances pyrimidine motif triplex-forming ability under physiological condition
Torigoe, Hidetaka
Sato, Norihiro
Nagasawa, Nobuyuki
JOURNAL OF BIOCHEMISTRY, 2012, 152 (01): : 17 - 26

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