The Role of the Pharmacist in Selecting the Best Choice of Medication Formulation in Dysphagic Patients

被引:1
|
作者
Zuccari, Guendalina [1 ]
Macis, Sara [2 ]
Alfei, Silvana [1 ]
Marchitto, Leonardo [3 ]
Russo, Eleonora [1 ]
机构
[1] Univ Genoa, Dept Pharm, Viale Cembrano, I-16148 Genoa, Italy
[2] San Paolo Hosp, Hosp Pharm, Dept Tech Hlth, Via Genova, I-17100 Savona, Italy
[3] Univ Bologna, Dept Sci Qual Life, Corso DAugusto 237, I-47921 Rimini, Italy
来源
JOURNAL OF PERSONALIZED MEDICINE | 2022年 / 12卷 / 08期
关键词
hospital pharmacy; dysphagic patients; off-label prescriptions; solid oral formulations; compounding pharmacist; patient safety; ENTERAL NUTRITION; FEEDING TUBES;
D O I
10.3390/jpm12081307
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Usually, the administration of drugs by feeding tube in dysphagic patients involves handling of marketing licenses outside their term, due to the lack of suitable formulations. This circumstance has put health professionals in the dilemma of choosing the formulation whose manipulation possibly does not alter the effectiveness of the drug. In this regard, a practical guide providing indications on the prescription, handling, and administration of drugs through enteral feeding tube could be of paramount utility. For this purpose, we have considered the 1047 solid oral pharmaceutical forms included in the formulary of San Paolo Hospital (Savona, Italy). From our analysis, it emerges that 95% of medicinal products are worryingly used off-label and 40% have to be managed by the hospital pharmacists without having suitable indications by either the manufacturers or by literature studies. To fill this gap, we have compiled a detailed table containing missing indications derived from pharmacist expertise and evidence-based practices, with the aim that the sharing of our procedures will contribute to make uniform pharmacological therapies from one hospital to another. This study will allow doctors to have easy access to information on drugs that can be prescribed and nurses to become familiar only with the pharmaceutical forms that can be administered.
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页数:64
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