A chemoselective photolabile protecting group for aldehydes

被引：2
|
作者：
Xu, Jing [1 ]
Zhang, Shouguo [1 ]
Yang, Hongpeng [1 ]
Wen, Xiaoxue [1 ]
Peng, Tao [1 ]
Xu, Kaijun [2 ]
Wang, Gang [1 ]
Wang, Lin [1 ]
机构：
[1] Beijing Inst Radiat Med, 27 Taiping Rd, Beijing 100850, Peoples R China
[2] China Pharmaceut Univ, Sch Sci, Nanjing 211198, Peoples R China
来源：
TETRAHEDRON LETTERS | 2020年 / 61卷 / 14期
基金：
中国国家自然科学基金;
关键词：
Photolabile protecting group; Photodeprotection; Aldehyde compound; O-nitrobenzyl group; LIGHT;
D O I：
10.1016/j.tetlet.2020.151709
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new and high-efficiency photolabile protecting group (PLPG) for aldehydes is described. The PLPG was introduced to aldehydes by using a Lewis acid. Results showed that the PLPG can be released rapidly and smoothly under ultraviolet (UV) irradiation with high efficiency and low cost. This PLPG can easily synthesized and also be selectively protect aldehydes in the presence of ketones. (C) 2020 Elsevier Ltd. All rights reserved.
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页数：4
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