Design and synthesis of a novel series of matrix metalloproteinase inhibitors with high selectivity for MMP-3.

被引：0
|
作者：
Dack, KN [1 ]
Dickinson, RP [1 ]
Lewis, ML [1 ]
Whitlock, GA [1 ]
机构：
[1] Pfizer Global Res & Dev, Discovery Chem, Sandwich, Kent, England
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 222卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
260-MEDI
引用
收藏
页码：U684 / U684
页数：1
相关论文
共 50 条
  • [1] Design and synthesis of novel metalloproteinase inhibitors
    Nakatani, Shingo
    Ikura, Masahiro
    Yamamoto, Shingo
    Nishita, Yoshitaka
    Itadani, Satoshi
    Habashita, Hiromu
    Sugiura, Tsuneyuki
    Ogawa, Koji
    Ohno, Hiroyuki
    Takahashi, Kanji
    Nakai, Hisao
    Toda, Masaaki
    BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (15) : 5402 - 5422
  • [2] Design and synthesis of MMP inhibitors with appended fluorescent tags for imaging and visualization of matrix metalloproteinase enzymes
    Freskos, John N.
    Asmelash, Bethel
    Gaston, Kimberly R.
    Karwa, Amol
    Marzan, Tim A.
    Nickols, Maureen A.
    Rogers, Thomas E.
    Schoenstein, Tasha
    Sympson, Carolyn J.
    Vu, Bich
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (20) : 5566 - 5570
  • [3] Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors
    Cheng, Xian-Chao
    Wang, Qiang
    Fang, Hao
    Tang, Wei
    Xu, Wen-Fang
    BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (10) : 5398 - 5404
  • [4] Design, synthesis and preliminary evaluation of novel pyrrolidine derivatives as matrix metalloproteinase inhibitors
    Cheng, Xian-Chao
    Wang, Qiang
    Fang, Hao
    Tang, Wei
    Xu, Wen-Fang
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (10) : 2130 - 2139
  • [5] Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors
    Chen, Chen
    Yang, Xinying
    Fang, Hao
    Hou, Xuben
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 181
  • [6] A novel series of matrix metalloproteinase inhibitors for the treatment of inflammatory disorders
    Baxter, AD
    Bird, J
    Bhogal, R
    Massil, T
    Minton, KJ
    Montana, J
    Owen, DA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (07) : 897 - 902
  • [7] Design and synthesis of dual inhibitors for matrix metalloproteinase and cathepsin
    Yamamoto, M
    Ikeda, S
    Kondo, H
    Inoue, S
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (03) : 375 - 378
  • [8] Design and synthesis of piperazine-based matrix metalloproteinase inhibitors
    Cheng, MY
    De, B
    Pikul, S
    Almstead, NG
    Natchus, MG
    Anastasio, MV
    McPhail, SJ
    Snider, CE
    Taiwo, YO
    Chen, LY
    Dunaway, CM
    Gu, F
    Dowty, ME
    Mieling, GE
    Janusz, MJ
    Wang-Weigand, S
    JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (03) : 369 - 380
  • [9] Novel Matrix Metalloproteinase-9 (MMP-9) Inhibitors in Cancer Treatment
    Rashid, Zainab Ahmed
    Bardaweel, Sanaa K.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (15)
  • [10] The synthesis and biological activity of a novel series of diazepine MMP inhibitors
    Levin, JI
    DiJoseph, JF
    Killar, LM
    Sung, A
    Walter, T
    Sharr, MA
    Roth, CE
    Skotnicki, JS
    Albright, JD
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (19) : 2657 - 2662
12345