An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold

被引:88
|
作者
Naimi-Jamal, M. Reza [1 ]
Mashkouri, Sara [1 ]
Sharifi, Ali [2 ]
机构
[1] Iran Univ Sci & Technol, Res Lab Green Organ Synth, Dept Chem, Tehran 16846, Iran
[2] Chem & Chem Engn Res Ctr Iran, Tehran, Iran
关键词
2-Amino-4H-chromenes; Solvent-free; Multicomponent reactions; Domino reactions; Knoevenagel-Michael addition; POT 3-COMPONENT CONDENSATION; THROUGHPUT SCREENING ASSAY; AQUA MEDIATED SYNTHESIS; SUBSTITUTED; 2-AMINO-4H-CHROMENES; HETEROCYCLIC SYNTHESIS; TERMINAL ALKYNES; GREEN SYNTHESIS; 2-AMINO-2-CHROMENES; DERIVATIVES; CATALYST;
D O I
10.1007/s11030-010-9246-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Solvent-free one-pot synthesis of 2-amino-4H-chromene scaffold is described in a very simple, efficient, and environmentally benign method using sodium carbonate as a cheap and non-toxic catalyst with up to excellent yields.
引用
收藏
页码:473 / 477
页数:5
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