This paper presents a novel Peristaltic Micro Pump with a twofold intrinsic Normally-Closed mechanism (PMP-NC2). It is based on a modular concept with a low cost disposable microfluidic chip and a re-usable actuator unit. The normally-closed mechanism prevents fluid flow without power consumption in the stand-by mode for pressures up to 150 kPa. Together with the backpressure independent pumping performance up to 80 kPa this results in a fail-safe and precise micropump. The addressed range of pump rates is up to 100 mu L/min. Due to the symmetrical setup, bi-directional pumping is possible and also air bubble tolerance is demonstrated. This results from the very low dead volume per pump chamber of only 230 nL, which leads to a complete transport of the air bubbles through the pump.
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Mt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USAMt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Jacobs, Michelle M.
Murray, Jacinta
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Mt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USAMt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Murray, Jacinta
Byrd, Desiree A.
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Mt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Mt Sinai, Dept Psychiat, Icahn Sch Med, New York, NY 10029 USAMt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Byrd, Desiree A.
Hurd, Yasmin L.
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Mt Sinai, Dept Psychiat, Icahn Sch Med, New York, NY 10029 USA
Mt Sinai, Dept Neurosci, Icahn Sch Med, New York, NY 10029 USAMt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Hurd, Yasmin L.
Morgello, Susan
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Mt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA
Mt Sinai, Dept Neurosci, Icahn Sch Med, New York, NY 10029 USA
Mt Sinai, Dept Pathol, Icahn Sch Med, New York, NY 10029 USAMt Sinai, Dept Neurol, Icahn Sch Med, New York, NY 10029 USA