Emerging biomarkers for the detection of cardiovascular diseases

被引:24
|
作者
Thupakula, Sreenu [1 ]
Nimmala, Shiva Shankar Reddy [1 ]
Ravula, Haritha [2 ]
Chekuri, Sudhakar [3 ]
Padiya, Raju [1 ]
机构
[1] Osmania Univ, Dept Biochem, Hyderabad 500007, Telangana, India
[2] Univ Hyderabad, Dept Plant Sci, Hyderabad 500019, Telangana, India
[3] Osmania Univ, Dept Genet, Hyderabad 500007, Telangana, India
来源
EGYPTIAN HEART JOURNAL | 2022年 / 74卷 / 01期
关键词
Biomarkers; Biomolecular systems; Cardiovascular disease; Cardiac markers; Diagnosis; Therapeutics; GELATINASE-ASSOCIATED LIPOCALIN; CORONARY-ARTERY-DISEASE; ALPHA-HYDROXYBUTYRATE DEHYDROGENASE; GROWTH-DIFFERENTIATION FACTOR-15; HEART-FAILURE PATIENTS; SERUM URIC-ACID; REGIONAL PRO-ADRENOMEDULLIN; PHOSPHORYLASE ISOENZYME BB; BRAIN NATRIURETIC PEPTIDE; SHORT-TERM PROGNOSIS;
D O I
10.1186/s43044-022-00317-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The prevalence of cardiovascular disease (CVD) has been continuously increasing, and this trend is projected to continue. CVD is rapidly becoming a significant public health issue. Every year there is a spike in hospital cases of CVD, a critical health concern in lower- and middle-income countries. Based on identification of novel biomarkers, it would be necessary to study and evaluate the diagnostic requirements or CVD to expedite early detection. Main body: The literature review was written using a wide range of sources, such as well-known medical journals, electronic databases, manuscripts, texts, and other writings from the university library. After that, we analysed the specific markers of CVD and compiled a systematic review. A growing body of clinical research aims to identify people who are at risk for cardiovascular disease by looking for biomolecules. A small number of biomarkers have been shown to be useful and reliable in medicine. Biomarkers can be used for a variety of clinical applications, such as predicting heart disease risk, diagnosing disease, or predicting outcomes. As a result of the ability for a single molecule to act as a biomarker, its usefulness in medicine is expected to increase significantly. Conclusions: Based on assessing the current trends in the application of CVD markers, we discussed and described the requirements for the application of CVD biomarkers in coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other cardiovascular illnesses. Furthermore, the current review focuses on biomarkers for CVD and the procedures that should be considered to establish the comprehensive nature of the expression of biomarkers for cardiovascular illness.
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页数:17
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