Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction

被引:12
|
作者
Xie, Ruiman [2 ]
Fang, Min [2 ]
Zhou, Linjiang [1 ]
Fan, Shanghua [2 ]
Liu, Jianying [2 ]
Quan, Hongbo [2 ]
Luo, Man [2 ]
Qiu, Dongying [2 ]
机构
[1] Fudan Univ, Huashan Hosp, Dept Radiol, Shanghai 200040, Peoples R China
[2] Fudan Univ, Zhongshan Hosp, Dept Neurol & Gerontol, Shanghai 200032, Peoples R China
关键词
corticospinal tracts; Wallerian degeneration; fractional anisotropy; diffusion tensor imaging; neuroimaging; neural regeneration; PYRAMIDAL TRACT; ISCHEMIC-STROKE; AXON;
D O I
10.3969/j.issn.1673-5374.2012.12.004
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
To investigate the feasibility and time window of early detection of Wallerian degeneration in the corticospinal tract after middle cerebral artery infarction, 23 patients were assessed using magnetic resonance diffusion tensor imaging at 3.0T within 14 days after the infarction. The fractional anisotropy values of the affected corticospinal tract began to decrease at 3 days after onset and decreased in all cases at 7 days. The diffusion coefficient remained unchanged. Experimental findings indicate that diffusion tensor imaging can detect the changes associated with Wallerian degeneration of the corticospinal tract as early as 3 days after cerebral infarction.
引用
收藏
页码:900 / 905
页数:6
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