Mechanical behavior of hydroxyapatite-poly(lactic acid) hybrid porous scaffold

被引:11
|
作者
Zusho, Yu [1 ]
Kobayashi, Satoshi [1 ]
Osada, Toshiko [1 ]
机构
[1] Tokyo Metropolitan Univ, Fac Syst Design, Dept Mech Syst Engn, Tokyo, Japan
关键词
hydroxyapatite; coating; ploy(lactic acid); porous body; acoustic emission; COMPRESSIVE STRENGTH; ROBOCAST SCAFFOLDS; BONE; PERFORMANCE; FABRICATION;
D O I
10.1080/09243046.2020.1759183
中图分类号
TB33 [复合材料];
学科分类号
摘要
Although autologous bone is currently used for repairing bone defects, this method is highly invasive and poses a heavy burden on patients. Thus, the use of artificial bones has been expected. Among the artificial bone materials, bioactive hydroxyapatite (HA) has been attracting much attention. In this research, in order to overcome the problem such as low initial strength of artificial bone after implantation, poly(lactic acid) (PLA) was coated on HA unidirectional porous body prepared by freeze-casting method. In order to investigate the PLA coating method that most effectively improves the mechanical properties, the coating state of PLA was observed and the compression test was performed. As a result of the compression test of the HA-PLA composite porous body, Young's modulus and compressive strength were improved by 79% and 184% respectively at maximum. Furthermore, acoustic emission (AE) measurement was conducted to investigate the fracture behavior during the compression test, classifying the main fracture of HA and HA-PLA porous body as shear fracture.
引用
收藏
页码:587 / 602
页数:16
相关论文
共 50 条
  • [1] Novel fabrication method of porous poly(lactic acid) scaffold with hydroxyapatite coating
    Guo, Chao
    Guo, Xi
    Cai, Ning
    Dong, Yinsheng
    MATERIALS LETTERS, 2012, 74 : 197 - 199
  • [2] Preparation of a novel porous scaffold from poly(lactic-co-glycolic acid)/hydroxyapatite
    Nazarpak, Masoume Haghbin
    Pourasgari, Farzaneh
    Sarbolouki, Mohammandnabi
    ASIAN BIOMEDICINE, 2011, 5 (04) : 513 - 518
  • [3] Systematic evolution of a porous hydroxyapatite-poly(vinylalcohol)-gelatin composite
    Nayar, S
    Sinha, A
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2004, 35 (01) : 29 - 32
  • [4] Duplex surface modification of porous poly (lactic acid) scaffold
    Guo, Chao
    Cai, Ning
    Dong, Yinsheng
    MATERIALS LETTERS, 2013, 94 : 11 - 14
  • [5] Effect of Size on Degradation of Porous Poly (lactic acid) Scaffold
    Guo, Chao
    Sheng, Xiaobo
    Chu, Chenglin
    Dong, Yinsheng
    ADVANCED MATERIALS AND PROCESSES, PTS 1-3, 2011, 311-313 : 1741 - 1745
  • [6] Improved mechanical properties of hydroxyapatite whisker-reinforced poly(L-lactic acid) scaffold by surface modification of hydroxyapatite
    Fang, Zhou
    Feng, Qingling
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2014, 35 : 190 - 194
  • [7] Hybrid coating of hydroxyapatite and collagen within poly(D,L-lactic-co-glycolic acid) scaffold
    Li, Jiashen
    Yuan, Xiaoyan
    He, Fei
    Mak, Arthur F. T.
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2008, 86B (02) : 381 - 388
  • [8] Homogeneously dispersed composites of hydroxyapatite nanorods and poly(lactic acid) and their mechanical properties and crystallization behavior
    Zhang, Rong
    Hu, Hailong
    Liu, Yang
    Tan, Junjun
    Chen, Wenqi
    Ying, Cheng
    Liu, Qingting
    Fu, Xudong
    Hu, Shengfei
    Wong, Ching Ping
    COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 2020, 132
  • [9] Ultrasonication-Induced Modification of Hydroxyapatite Nanoparticles onto a 3D Porous Poly(lactic acid) Scaffold with Improved Mechanical Properties and Biocompatibility
    Si, Junhui
    Lin, Jixin
    Su, Chen
    Yu, Shengrui
    Cui, Zhixiang
    Wang, Qianting
    Chen, Wenzhe
    Turng, Lih-Sheng
    MACROMOLECULAR MATERIALS AND ENGINEERING, 2019, 304 (07)
  • [10] Mechanical and Materialistic Characterization of Poly Lactic Acid/Zeolite/Hydroxyapatite Composites
    Ayyanar, C. Balaji
    Marimuthu, K.
    Sridhar, N.
    Mugilan, T.
    Alqarni, Sara A. A.
    Katowah, Dina F. F.
    Sanjay, M. R.
    Siengchin, Suchart
    JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2023, 33 (09) : 2743 - 2751