A graph is called very well-covered if it is unmixed without isolated vertices such that the cardinality of each minimal vertex cover is half the number of vertices. We first prove that a very well-covered graph is Cohen-Macaulay if and only if it is vertex decomposable. Next, we show that the Castelnuovo-Mumford regularity of the quotient ring of the edge ideal of a very well-covered graph is equal to the maximum number of pairwise 3-disjoint edges. (C) 2011 Elsevier B.V. All rights reserved.