Synthesis of nanorattles with layered double hydroxide core and mesoporous silica shell as delivery vehicles

被引：54

作者：

Liu, Jian ^{[1
]}

Harrison, Ryan ^{[1
]}

Zhou, Ji Zhi ^{[1
]}

Liu, Ting Ting ^{[1
]}

Yu, Chengzhong ^{[1
]}

Lu, Gao Qing ^{[1
]}

Qiao, Shi Zhang ^{[1
]}

Xu, Zhi Ping ^{[1
]}

机构：

[1] Univ Queensland, ARC Ctr Excellence Funct Nanomat, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2011年 / 21卷 / 29期

基金：

澳大利亚研究理事会;

关键词：

NANOPARTICLES; NANOSTRUCTURES;

D O I：

10.1039/c1jm12054a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This paper describes the controlled synthesis and release properties of MgAl-layered double hydroxide (LDH) mesoporous silica nanorattles. Both LDH and LDH intercalated with fluorescein isothiocyanate (FITC) were coated with mesoporous silica shells to form nanorattles. As-obtained LDH mesoporous silica composites were found to possess the structural features of both LDH and mesoporous silica. The release properties of the nanorattles were evaluated using FITC as the model fluorophore. The LDH-based nanorattles showed controlled release profiles of FITC, which can be attributed to the unique rattle-type structure. The controlled synthesis of LDH mesoporous silica nanorattles thus provides a new opportunity for future development of delivery vehicles.

引用

页码：10641 / 10644

页数：4

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