Palladium-catalyzed cascade reactions of highly activated olefins

In this account, we describe the use of highly activated olefins for palladium-catalyzed reactions. Particularly noteworthy is the creation of new processes using such activated olefins and the efficiency of those processes in building carbon-carbon and carbon-heteroatom bonds under relatively mild conditions. This account is aimed at creating awareness among organic chemists about the use of highly activated olefins in catalytic reactions. 1 Introduction 2 Bisfunctionalization of Highly Activated Olefins 2.1 Alkoxyallylation 2.2 Aminoallylation 2.3 Cyanoallylation ]2.4 Bis-allylation 2.5 Propargylallylation 2.6 Acetonation-Allylation 2.7 Alkylallylation 2.8 Hydroallylation 2.9 Synthesis of Dienes/Cope Rearrangement 3 Conclusion