Transcatheter heart valve interventions: where are we? Where are we going?

被引：52

作者：

Prendergast, Bernard D. ^{[1
]}

Baumgartner, Helmut ^{[2
]}

Delgado, Victoria ^{[3
]}

Gerard, Olivier ^{[4
]}

Haude, Michael ^{[5
]}

Himmelmann, Anders ^{[6
]}

Iung, Bernard ^{[7
]}

Leafstedt, Matthew ^{[8
]}

Lennartz, Jasmine ^{[8
]}

Maisano, Francesco ^{[9
]}

Marinelli, Elena Andreassi ^{[10
]}

Modine, Thomas ^{[11
]}

Mueller, Markus ^{[12
]}

Redwood, Simon R. ^{[1
]}

Roerick, Olaf ^{[13
]}

Sahyoun, Cherif ^{[14
]}

Saillant, Erika ^{[4
]}

Sondergaard, Lars ^{[15
]}

Thoenes, Martin ^{[16
]}

Thomitzek, Karen ^{[17
]}

Tschernich, Marion ^{[4
]}

Vahanian, Alec ^{[7
]}

Wendler, Olaf ^{[18
]}

Zemke, Evelyn Julia ^{[13
]}

Bax, Jeroen J. ^{[3
]}

机构：

[1] St Thomas Hosp, Dept Cardiol, Westminster Bridge Rd, London SE1 7EH, England

[2] Univ Hosp Muenster, Dept Cardiovasc Med, Div Adult Congenital & Valvular Heart Dis, Munster, Germany

[3] Leiden Univ, Med Ctr, Dept Cardiol, Albinusdreef 2, NL-2300 RC Leiden, Netherlands

[4] GE Healthcare, Chicago, IL USA

[5] Stadt Kliniken Neuss, Med Clin 1, Neuss, Germany

[6] AstraZeneca R&D, Gothenburg, Sweden

[7] Paris Diderot Univ, Bichat Hosp, AP HP, Cardiol Dept, Paris, France

[8] Medtronic, Tolochenaz, Switzerland

[9] Univ Spital Zurich, Klin Herz & Gefasschirurg, Zurich, Switzerland

[10] Dauchi Sankyo Europe GmbH, Munich, Germany

[11] CHRU Lille, Hop Cardiol, Dept Cardiovasc Surg, Lille, France

[12] Pfizer Inc, Berlin, Germany

[13] Siemens Healthineers, Erlangen, Germany

[14] Philips Healthcare, Best, Netherlands

[15] Univ Copenhagen, Rigshosp, Heart Ctr, Dept Cardiol, Copenhagen, Denmark

[16] Edwards Lifesci, Nyon, Switzerland

[17] Bayer AG, Berlin, Germany

[18] Kings Coll Hosp London, Dept Cardiothorac Surg, London, England

来源：

EUROPEAN HEART JOURNAL | 2019年 / 40卷 / 05期

关键词：

Heart valve disease; Transcatheter aortic valve replacement; Aortic valve; Mitral valve; Tricuspid valve; SEVERE AORTIC-STENOSIS; FUNCTIONAL MITRAL REGURGITATION; SEVERE TRICUSPID REGURGITATION; HIGH-RISK PATIENTS; IN-VALVE; CARDIOTHORACIC SURGERY; EUROPEAN ASSOCIATION; BIOPROSTHETIC VALVES; PERCUTANEOUS REPAIR; CARDIOLOGY ESC;

D O I：

10.1093/eurheartj/ehy668

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Transcatheter heart valve interventions have transformed the outcomes of patients with valvular heart disease (VHD) who are unfavourable candidates for surgery. Technological advances have allowed extension of these interventions to younger or lower risk patients and those with other forms of VHD and may in the future permit earlier treatment of VHD in less symptomatic patients or those with moderate disease. The balance of risks and benefits is likely to differ between lower and higher risk patients, and more evidence is needed to evaluate the net benefit of transcatheter technology in these groups As academic researchers clinicians industry and patient stakeholders collaborate to research these broader indications for transcatheter valve interventions, it is essential to address (i) device durability and deliverability, (ii) specific anatomical needs (e.g. bicuspid aortic valves, aortic regurgitation, mitral and tricuspid valve disease), (iii) operator training, and (iv) the reinforced importance of the multidisciplinary Heart Team.

引用

页码：422 / 440

页数：19

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