The peptide molecular links between the central nervous and the immune systems

被引：48

作者：

Siemion, IZ ^{[1
]}

Kluczyk, A ^{[1
]}

Cebrat, M ^{[1
]}

机构：

[1] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

来源：

AMINO ACIDS | 2005年 / 29卷 / 03期

关键词：

CNS-immune system molecular links; immunopeptides; neuropeptides; thymic peptides;

D O I：

10.1007/s00726-005-0231-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The central nervous system (CNS) and the immune system were for many years considered as two autonomous systems. Now, the reciprocal connections between them are generally recognized and very well documented. The links are realized mainly by various immuno- and neuropeptides. In the review the influence of the following immunopeptides on CNS is presented: tuftsin, thymulin, thymopoietin and thymopentin, thymosins, and thymic humoral factor. On the other side, the activity in the immune system of such neuropeptides as substance P, neurotensin, some neurokinins, enkephalins, and endorphins is discussed.

引用

页码：161 / 176

页数：16

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