With the rapid growth of human demands for nuclear energy, in response to the challenges of nuclear energy development, the world's major nuclear countries have started the R&D of advanced nuclear energy systems, in which new materials and new technologies are considered to play important roles. Nano-materials and nano-technologies, which have gain extensive attentions in recent years, have shown a wide range of potential applications in future nuclear energy system. In this paper, the basic research progresses of nano-materials and nano-technologies in advanced nuclear fuel fabrication, spent nuclear fuel reprocessing, nuclear waste disposal and nuclear environmental restoration is reviewed. Furthermore, the R&D trends of nano-materials and nano-technologies in future advanced nuclear energy system are discussed.