Transition metal catalysis for pharmaceutical intermediates and APIs

被引：2

作者：

Indolese, AF ^{[1
]}

Wasescha, D ^{[1
]}

Eisele, T ^{[1
]}

Bucher, C ^{[1
]}

机构：

[1] Rohner AG, CH-4133 Pratteln, Switzerland

来源：

CHIMIA | 2005年 / 59卷 / 1-2期

关键词：

asymmetric hydrogenation; carbonylation; custom synthesis; Suzuki coupling;

D O I：

10.2533/000942905777676966

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rohner AG, a medium-sized Swiss company, has moved from toll manufacturing of building blocks and starting materials to the custom manufacturing of intermediates and APIs for the life science industry. Therefore, Rohner AG has expanded its technology portfolio to new technologies such as transition metal catalysis. Examples for asymmetric hydrogenation, Suzuki coupling and carbonylation are provided. In addition, the necessary changes in equipment and project management are presented and discussed.

引用

页码：22 / 24

页数：3

共 50 条

[1] Transition metal catalysis of cationic intermediates and substrates
Watson, Mary P.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
[2] Transition Metal Catalysis Research in Pharmaceutical Organic Chemistry Foreword
Nemoto, Tetsuhiro
CHEMICAL & PHARMACEUTICAL BULLETIN, 2023, 71 (02) : 78 - 78
[3] Pharmaceutical intermediates - Clariant expands sterile APIs in France
Mullin, R
CHEMICAL WEEK, 2002, 164 (35) : 38 - 38
[4] ENANTIOSELECTIVE HOMOGENEOUS CATALYSIS INVOLVING TRANSITION-METAL ALLYL INTERMEDIATES
CONSIGLIO, G
WAYMOUTH, RM
CHEMICAL REVIEWS, 1989, 89 (01) : 257 - 276
[5] Pharmaceutical intermediates - 'Bad news' in APIs forces Siegfried to restructure
Scott, A
CHEMICAL WEEK, 2003, 165 (30) : 46 - 46
[6] Synthetic Development of Key Intermediates and Active Pharmaceutical Ingredients (APIs)
Laha, Joydev K.
Zhou, Jianrong Steve
SYNTHESIS-STUTTGART, 2024, 56 (04): : III - IV
[7] Gas-phase transition metal cluster catalysis: Energetics of reaction intermediates
Ervin, KM
Dogbevia, M
Angel, LA
Shi, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U273 - U273
[8] Metal–metal multiple bonded intermediates in catalysis
JOHN F BERRY
Journal of Chemical Sciences, 2015, 127 : 209 - 214
[9] Enamine/Transition Metal Combined Catalysis: Catalytic Transformations Involving Organometallic Electrophilic Intermediates
Afewerki, Samson
Cordova, Armando
TOPICS IN CURRENT CHEMISTRY, 2019, 377 (06)
[10] Enamine/Transition Metal Combined Catalysis: Catalytic Transformations Involving Organometallic Electrophilic Intermediates
Samson Afewerki
Armando Córdova
Topics in Current Chemistry, 2019, 377

← 1 2 3 4 5 →