Prediction of parameters c and a in reversed-phase high-performance liquid chromatography using retention parameters in gas liquid chromatography

被引：1
|
作者：
Wang, WL [1 ]
Zhang, XM
Lu, PZ
Deng, JQ
机构：
[1] Henan Coll Educ, Dept Chem, Zhengzhou 450003, Peoples R China
[2] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
来源：
ANALYTICAL LETTERS | 2001年 / 34卷 / 05期
关键词：
reversed-phase high-performance liquid chromatography; gas liquid chromatography; prediction; retention parameter;
D O I：
10.1081/AL-100103220
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The relationship of retention mechanism between gas liquid chromatography (GLC) and reversed-phase high-performance liquid chromatography (RP-HPLC) is discussed. A model to predict the retention parameters c and a in retention equation in RP-HPLC using retention parameters in GLC is established, and it is verified by experimental data. By comparing the interaction forces in GLC and RP-HPLC, it was found that the hydrogen-bonding interaction plays an important role in determining the retention mechanism of a solute in RP-HPLC, and the form of hydrogen-bonding is the eluent acting as hydrogen-bonding donor acidity and the solute acting as hydrogen-bonding acceptor basicity. The-refractive force is important in both GLC and RP-HPLC, but the dipole moment interaction can be ignored.
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页码：785 / 802
页数：18
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