A recent study by Forceville and colleagues evaluated the effect of high-dose selenium administration as a treatment for septic shock. The study was negative and conflicts with existing clinical data regarding selenium administration in critically ill patients. Perhaps the key to understanding the differences between these discrepant observations lies in considering the dose and timing of selenium administration.
机构:
UNIV STOCKHOLM, DEPT BIOCHEM, ARRHENIUS LABS NAT SCI, S-10691 STOCKHOLM, SWEDENUNIV STOCKHOLM, DEPT BIOCHEM, ARRHENIUS LABS NAT SCI, S-10691 STOCKHOLM, SWEDEN
BARBER, J
ANDERSSON, B
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机构:
UNIV STOCKHOLM, DEPT BIOCHEM, ARRHENIUS LABS NAT SCI, S-10691 STOCKHOLM, SWEDENUNIV STOCKHOLM, DEPT BIOCHEM, ARRHENIUS LABS NAT SCI, S-10691 STOCKHOLM, SWEDEN
机构:
Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada
Univ Hlth Network, Dept Med, Toronto, ON, Canada
Mt Sinai Hosp, Toronto, ON M5G 1X5, CanadaUniv Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada