Selenium supplementation in critically ill patients: Can too much of a good thing be a bad thing?

被引:40
|
作者
Heyland, Daren K. [1 ]
机构
[1] Kingston Gen Hosp, Clin Evaluat Res Unit, Kingston, ON K7L 2V7, Canada
来源
CRITICAL CARE | 2007年 / 11卷 / 04期
关键词
D O I
10.1186/cc5975
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A recent study by Forceville and colleagues evaluated the effect of high-dose selenium administration as a treatment for septic shock. The study was negative and conflicts with existing clinical data regarding selenium administration in critically ill patients. Perhaps the key to understanding the differences between these discrepant observations lies in considering the dose and timing of selenium administration.
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页数:3
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